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The Use of ICP-MS and IC-ICP-MS in Environmental and Exposure Assesssment
Citation:
CREED, JOHN T., T. Pinyayev, K. KUBACHKA, C. GALLAWA, P. A. CREED, M. J. KOHAN, K. HERBIN-DAVIS, AND D. J. THOMAS. The Use of ICP-MS and IC-ICP-MS in Environmental and Exposure Assesssment. Presented at Applied Spectroscopy Society Meeting, Cullowhee, NC, February 09, 2010.
Impact/Purpose:
Develop analytical approaches to quantify reactive intermediates within the metabolic pathway that biotransforms inorganic arsenic to DMA(V). The ability to quantify these species will enhance the mode of action (within NHEERL) and the bioavailability / bioaccessibility research (within NERL).
Description:
OVERVIEW: Application of collision/reaction cell interference reduction technology for the minimization of polyatomic interferences in environmental matrices. Improved risk assessments through the use of arsenic speciation approaches that estimate the bio-accessibility associated with the exposure. Presystemic bio-transformation of arsenic oxides and their exposure assessment implications.