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Differential Toxicity and Accumulation of Fipronil Enantiomers in the Fathead Minnow (Pimephales promelas)
Citation:
Baird, S., A. W. GARRISON, J. K. AVANTS, AND M. C. Black. Differential Toxicity and Accumulation of Fipronil Enantiomers in the Fathead Minnow (Pimephales promelas). Presented at 2010 Land Grant and Sea Grant National Water Conference, Hilton Head Island, SC, February 21 - 25, 2010.
Impact/Purpose:
The main objective of this research is to determine the environmental occurrences, fate, and exposure of the enantiomers of selected chiral pesticides and other chiral organic pollutants. Chiral compounds, which exist as mixtures of enantiomers, include important environmental pollutants.
Description:
Fipronil is a chiral insecticide applied as a racemate of two enantiomers. Because of its high log Koc, fipronil will be found primarily in sediments of aquatic environments. Although a number of studies have examined toxicity in aquatic invertebrates, data on enantioselective toxicity and bioaccumulation in fish are limited. We characterized the toxicity of fipronil racemate and enantiomers in acute and subchronic aquatic toxicity experiments and measured bioaccumulation of fipronil from spiked sediments in chronic exposures with larval fathead minnows (Pimephales promelas).