Cumulative Aggregate Risk Evaluation Software
Description:
CARES is a state-of-the-art software program designed to conduct complex exposure and risk assessments for pesticides, such as the assessments required under the 1996 Food Quality Protection Act (FQPA). CARES was originally developed under the auspices of CropLife America (CLA), which conceived the project, provided funding, and oversaw the program’s evolution. Scientific and technical contributions to the program’s development came from a broad team of experts, including scientists from CLA’s member companies and staff, consulting companies, and the USEPA and USDA. With its transfer to the ILSI Research Foundation, the CARES program and source code will continue to be publicly available at no charge. Also, the full range of stakeholders will be invited to contribute to the technical and scientific advancement of CARES.
Record Details:
Record Type:MODEL
Record Released:09/22/2009
Record Last Revised:10/08/2009
Record ID:
213910
Keywords:
Residue, consumption, diet, commodity, chemical, Monte Carlo, probabilistic, stochastic, random, exposure, risk, MOE, RfD, NOAEL, Sub-population,
Model Keywords:
Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), Frequency and Duration, Stochastic, providing a distribution of values for key model outputs, Air, Water (e.g., surface water, ground water), Ground (e.g., soil, sediment), Chemical (e.g., organic, inorganic, toxics),
Model Detail:
Model Evaluation
:http://www.epa.gov/scipoly/SAP/meetings/2002/april/caresmeetingminutes.pdf
Model URL
:http://cares.ilsi.org
Model Guidance Documents
:http://cares.ilsi.org/CaresGuides.htm
Model Download Information
:http://cares.ilsi.org/careslicense.htm
modelcontactinfo
:Agency Contact:
David Hrdy
Health Effects Division
Office of Pesticide Programs
Office of Prevention, Pesticides, and Toxic Substances
US Environmental Protection Agency
hrdy.david@epa.gov
703-305-6990
Developer Contact:
Dr. Muhilan Pandian
http://www.infoscientific.com
2240 Village Walk Drive, Suite 2310
Henderson, NV 89052
p702.368.5577
f702.368.5575
muhilan@infoscientific.com
Model Inputs
:Residue in parts per million to calculate exposure, NOAEL or Reference dose to calculate risk.
http://cares.ilsi.org/NR/rdonlyres/FA933FF2-133F-4F56-B97A-096DA49525E4/0/6QRG_rev20Sep04.pdf
Model Outputs
:Exposure in mg/kg/day or mg/day. Risk in percent of the Reference Dose and Margin of Exposure when using a NOAEL.
otheruserdocs
:http://cares.ilsi.org/CARESInfo.htm
Model Computer Requirements:
Model Operating Systems Needs
:Microsoft© Windows 2000 (SP3 or higher), or XP.
Model Hardware Needs
:For CARES installation, it is recommended that you have at least
- A Pentium (1.0 GHz or faster CPU) with 512 MB of RAM
- A video display capable of 1024 by 768 with at least 256 colors
- At least 20 GB of free hard disk space
other_req
:CARES requires installation of certain Microsoft© components prior to its installation. These components are MDAC and
Jet. Depending on your system configuration, you may not need mdac.exe and/or jet.exe. The CARES installation process will determine which package is needed (if any) and install automatically.