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An Approach To Using Toxicogenomic Data In U.S. EPA Human Health Risk Assessments: A Dibutyl Phthalate Case Study (Final Report, 2010)
Citation:
U.S. EPA. An Approach To Using Toxicogenomic Data In U.S. EPA Human Health Risk Assessments: A Dibutyl Phthalate Case Study (Final Report, 2010). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-09/028F, 2009.
Impact/Purpose:
The National Center for Environmental Assessment (NCEA) prepared this document for the purpose of describing and illustrating an approach for using toxicogenomic data in risk assessment.
Description:
EPA announced the availability of the final report, An Approach to Using Toxicogenomic Data in U.S. EPA Human Health Risk Assessments: A Dibutyl Phthalate Case Study. This report outlines an approach to evaluate genomic data for use in risk assessment and a case study to illustrate the approach. The dibutyl phthalate (DBP) case study example focuses on male reproductive developmental effects and the qualitative application of genomic data because of the available data on DBP. The case study presented in this report is a separate activity from any of the ongoing IRIS human health assessments for the phthalates.
URLs/Downloads:
U.S. EPA. An Approach to Using Toxicogenomic Data in U.S. EPA Human Health Risk Assessments: A Dibutyl Phthalate Case Study (Final Report) 2009. EPA/600/R-09/028F, 2009. (PDF, 240 pp, 6715 KB, about PDF)FR Notice: Jan 13, 2010
