Science Inventory

Human Health Research Program: Systems biological approaches

Impact/Purpose:

HH MYP

Description:

Research using systems analytic approaches to integrate biological and toxicological data across scales of biological organization (e.g. molecular, cellular, tissue, organ, full body, population), with the goal of identifying toxicity pathways, biomarkers, and bioindicators for application to risk assessment. Examples of this include research and modeling to build virtual tissues, such as the virtual liver or virtual embryo projects, efforts to build biologically-based dose-response models, and some aspects of physiologically-based pharmacokinetic modeling.

Record Details:

Record Type:PROJECT
Start Date:04/30/2009
Completion Date:04/30/2009
OMB Category:Other
Record ID: 210803