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ORD research and results using biological end points to detect exposures to contaminants of emerging concern
Citation:
LAZORCHAK, J. M., D. C. BENCIC, A. D. BIALES, M. KOSTICH, A. BATT, E. L. QUINLAN, H. Poynton, MARK E. SMITH, H. J. HARING, K. Hammer, AND B. Armstrong. ORD research and results using biological end points to detect exposures to contaminants of emerging concern. Presented at SWIMS Conference, Chicago, IL, February 09 - 11, 2009.
Impact/Purpose:
This presentation will provide a brief overview of the projects where QPCR gene expresson techniques using male and female fathead minows, daphnia microarrays and some new approaches using bacteria and algae, to detect the presence of CECs in the environment.
Description:
For the past nine years the Ecological Exposure Research Division (EERD) has been developing methods for the assessment of EDCs and other contaminants of emerging concern (CECs). These methods include genomic techniques for detecting the presence and potential exposure to human pharmaceutical estrogenic compounds such as ethynyl estradiol and veterinary pharmaceutical androgenic compounds used in beef feedlots such as trenbolone, bacterial and algal endpoints to detect antibiotics such as tetracycline and antimicrobial personal care products such as triclosan. In addition, EERD is also working on methods for assessing the detection and exposure of invertebrates to nanomaterials such as Nano Ag and ZnO using Daphnia magna and Hyalella azteca microarrays.