EPA Science Inventory

Environmental Carcinogens and Regulation

Citation:

PRESTON, J. Environmental Carcinogens and Regulation. Chapter 1, Simon J Wood (ed.), Encyclopedia of Environmental Health. Elsevier: Oxford, OXFORD, Uk, , 327–335, (2011).

Description:

Book chapter in Encyclopedia of Environmental Health

Purpose/Objective:

The history of chemical carcinogenis, involving both environmental and occupational exposures, covers a thousand or more years. In contrast, the regulation of such exposures has a much shorter history, covering about a hundred years in one form or another; with the more rigorous process currently employed being initiated about 50 years ago. It is perhaps surprising that even though there were very clear and severe adverse health outcomes associated with exposure to scientific chemicals or mixtures, the approach used to reduce the level of such outcomes was avoidance of exposure rather than reduction in exposure levels themselves. The path to a formal regulatory framework has been a difficult one, inevitably involving the debate on just what is “a safe level of exposure” and what is “an acceptable risk.” This chapter will provide some discussion of how regulatory standards that are protective against risk are set currently, and might in the future be established. Such a discussion is built on the premise that at least for cancer, regulatory decisions (within the U.S. EPA and other international organizations) are based largely on quantitative risk assessment.

URLs/Downloads:

B9780444522726000295   Exit

Record Details:

Record Type: DOCUMENT (BOOK CHAPTER)
Projected Completion Date: 01/01/2010
Record Last Revised: 08/08/2014
Record Created: 12/10/2008
Record Released: 12/10/2008
OMB Category: Other
Record ID: 202043

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LAB

ASSOCIATE DIRECTOR FOR HEALTH

IMMEDIATE OFFICE