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Chapter 11.18 - Neuroendocrine Control of Female Reproduction.
Citation:
FRAITES, M. P., T. E. STOKER, J. M. GOLDMAN, AND R. L. COOPER. Chapter 11.18 - Neuroendocrine Control of Female Reproduction. 2nd Edition, Chapter 18, Charlene A. McQueen (ed.), Comprehensive Toxicology. Elsevier: Oxford, OXFORD, Uk, 11:367-379, (2010).
Impact/Purpose:
This book chapter reviews the current state of the literature for studies investigating the neuroendocrine contro, of female reproduction
Description:
The hypothalamus and pituitary are known to play roles in reproductive function. A growing body of evidence indicates that environmental toxicants can alter female reproductive function by disrupting hypothalamic control of the pituitary and subsequently the endocrine control of ovarian function. This chapter will review the current literature on the effects of environmental toxicants on hypothalamic regulation of pituitary hormone secretion. The impact of toxicant exposures during critical periods of the estrous cycle as well as the concept of acquired tolerance following chronic exposure to specific toxicants will also be discussed.
