EPA Science Inventory

IRIS TOXICOLOGICAL REVIEW OF HEXAVALENT CHROMIUM (INTERAGENCY SCIENCE CONSULTATION DRAFT)

Notice:

As per the May 21, 2009, IRIS process, all comments received from federal agencies and White House offices on draft IRIS assessments will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Hexavalent Chromium and the draft charge to external peer reviewers are posted on this site.

Citation:

U.S. EPA. IRIS TOXICOLOGICAL REVIEW OF HEXAVALENT CHROMIUM (INTERAGENCY SCIENCE CONSULTATION DRAFT). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-10/004C, 2010.

Description:

On Septemeber 30, 2010, the draft Toxicological Review of Hexavalent Chromium and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process, introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Hexavalent Chromium and the charge to external peer reviewers are posted on this site.

Purpose/Objective:

EPA is undertaking a new health assessment for hexavalent chromium for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS and IRIS Summary of hexavalent chromium that will be entered on the IRIS database. IRIS is an EPA database containing scientific information on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information which can be combined with exposure assessment information to evaluate potential public health risks associated with environmental contaminants. The IRIS database is relied on for the development of risk assessments, site-specific environmental decisions, and rule making.

URLs/Downloads:

NTP Comments of the Review of Hexavalent Chromium   (PDF,2 pp, 407 KB,  about PDF)

Charge to External Reviewers (Interagency Science Consultation Draft)   (PDF,2 pp, 21 KB,  about PDF)

ATSDR Comments of the Review of Hexavalent Chromium   (PDF,2 pp, 23 KB,  about PDF)

OMB Comments of the Review of Hexavalent Chromium   (PDF,4 pp, 33 KB,  about PDF)

DOD Comments of the Review of Hexavalent Chromium   (PDF,15 pp, 137 KB,  about PDF)

DOD Comments of the charge questions for the Review of Hexavalent Chromium   (PDF,2 pp, 22 KB,  about PDF)

Toxicological Review of Hexavalent Chromium (Interagency Science Consultation Draft)   (PDF,260 pp, 1851 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (IRIS ASSESSMENT)
Projected Completion Date: 05/27/2011
Record Last Revised: 01/28/2014
Record Created: 10/30/2008
Record Released: 10/30/2008
OMB Category: Influential
Record ID: 200316

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT

IMMEDIATE OFFICE

INTEGRATED RISK INFORMATION STAFF