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Histopathologic Effects in Marine Fish Treated with Estrogens or an Aromatase Inhibitor
Citation:
ZAROOGIAN, J. E., D. B. HOROWITZ, J. FOURNIE, R. E. GUTJAHR-GOBELL, AND M. MILLS. Histopathologic Effects in Marine Fish Treated with Estrogens or an Aromatase Inhibitor. Presented at SETAC North American 29th Annual Meeting, Tampa, FL, November 16 - 20, 2008.
Impact/Purpose:
The purpose of this study was to histopathologically compare and evaluate the effect of endocrine-disrupting chemicals in the liver, gonad and kidney tissues of two species of treated fish.
Description:
Endocrine-disrupting chemicals, such as the estrogens estradiol (E2) and ethinylestradiol (EE2) , have been reported to affect fish reproduction. Androstatrienedione (ATD) is a known aromatase inhibitor which inhibits the conversion of testosterone to estradiol. The intent of this study was to histopathologically compare and evaluate the effect of endocrine-disrupting chemicals (EDCs) which alter fish reproduction in the liver, gonad, and kidney tissues of two species of treated fish.