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A QUICK OVERVIEW OF MASS SPECTROMETRY, NEGATIVE IONS, AND TOXAPHENE DETERMINATION (PROPOSED METHOD 8276)
Citation:
BRUMLEY, W. C. A QUICK OVERVIEW OF MASS SPECTROMETRY, NEGATIVE IONS, AND TOXAPHENE DETERMINATION (PROPOSED METHOD 8276). Presented at LTIG Conference, Denver, CO, April 10, 2008.
Impact/Purpose:
Presentation
Description:
A new method for toxaphene and toxaphene congener determination has been proposed by OSW as the response to an internal report from the OIG relative to toxaphene determination. In the course of this development, ORD was asked to prepare a new GC/NIMS protocol for 8081 analytes that included toxaphene, toxaphene congeners, chlordane, and organochlorine pesticides. This presentation explains some of the mass spectrometry principles behind NIMS and sketches the implementation of this approach to the determination of toxaphene congeners. The new methodology as far as SW-846 is concerned centers on the use of chemical ionization (methane reagent gas) conditions with the primary ionization resulting from electron attachmentor dissociative electron capture processes in the negative ion mode. OSW has narrowed the immediate concern to toxaphene congener determination and has decided to promulgate newguidance as Method 8276.