You are here:
U.S. EPA High-Field NMR Facility with Remote Accessibility
Citation:
TENG, Q., D. R. EKMAN, W. Huang, W. M. HENDERSON, AND T. W. COLLETTE. U.S. EPA High-Field NMR Facility with Remote Accessibility. Presented at EPA Science Forum, Washington, DC, May 20 - 22, 2008.
Impact/Purpose:
The objective of the metabolism subtask is to elucidate the kinetics, mechanisms and products of xenobiotic metabolism, using both in vitro and in vivo systems, to understand and model the exposure of the critical toxicant.
Description:
EPA’s High-Field Nuclear Magnetic Resonance Research Facility housed in Athens, GA has two Varian 600 MHz NMR spectrometers used for conducting sophisticated experiments in environmental science. Off-site users can ship their samples and perform their NMR experiments remotely from their desktops via secure internet connection. In collaboration with other Divisions in ORD/NERL, ORD/NHEERL, ORD/NCCT, various other Federal labs (PNNL, NIH/NCI, US Army Corp of Engineers), several Universities (UGA, UF, OGI, Purdue), and industry (Dow Chemical), the initial focus of the facility is metabolomics research to improve chemical exposure assessments, and structure biology research The facility is an ORD-wide resource, and we are inviting all EPA investigators to consider using the state-of-the-art NMR instrumentation in their work. After completing training provided by ERD researchers, any EPA scientist may independently operate the NMR spectrometers either on-site or remotely. The facility also offers access to Dr. Teng’s broad expertise in NMR experimental design and data interpretation. Remote operation of the NMR spectrometers will be demonstrated at the Science Forum.