EPA Science Inventory

IRIS Toxicological Review of Acrylamide (External Review Draft)

Notice:

In December 2007, EPA released the draft report,Toxicological Review for Acrylamide, for public comment and external peer review (step 5 of the IRIS Assessment Development Process. EPA's Science Advisory Board (SAB) conducted the peer review which was previously announced in a February 1, 2008 Federal Register Notice. Subsequent to the SAB review, an external letter peer consultation of methodology used to derive the internal dose was conducted. The report from this review is now available.

Citation:

U.S. EPA. IRIS Toxicological Review of Acrylamide (External Review Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-07/009A.

Description:

EPA has conducted a peer review by EPA’s Science Advisory Board (SAB) of the scientific basis supporting the human health hazard and dose-response assessment of acrylamide that once finalized will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that the science is used credibly and appropriately in derivation of the dose-response assessments and toxicological characterization.

Purpose/Objective:

The draft Toxicological Review of Acrylamide provides scientific support and rationale for the hazard identification and dose-response assessment pertaining to a chronic exposure to acrylamide.

URLs/Downloads:

FR Notice: Dec 28, 2007   Exit

Consolidated Comments from the External Peer Review (Final)   (PDF,30 pp, 207 KB,  about PDF)

Toxicological Review of Acrylamide (CAS No. 79-06-1) In Support of Summary Information on the Integrated Risk Information System (IRIS) External Review Draft   (PDF,377 pp, 1556 KB,  about PDF)

AGENCY RESPONSE

FR Notice: Feb 1, 2008   Exit

Record Details:

Record Type: DOCUMENT (IRIS ASSESSMENT)
Start Date: 03/22/2010
Completion Date: 03/22/2010
Record Last Revised: 09/25/2014
Record Created: 12/17/2007
Record Released: 12/17/2007
OMB Category: Highly Influential
Record ID: 187729

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR ENVIRONMENTAL ASSESSMENT

IMMEDIATE OFFICE