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IRIS Toxicological Review of Acrylonitrile (Interagency Science Consultation Draft)
Citation:
U.S. EPA. IRIS Toxicological Review of Acrylonitrile (Interagency Science Consultation Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-08/013C, 2011.
Impact/Purpose:
The Toxicological Review of Acrylonitrile provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to acrylonitrile.
Description:
On June 30, 2011, the draft Toxicological Review of Acrylonitrile and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process (May 2009), introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Acrylonitrile and the charge to external peer reviewers are posted on this site.
URLs/Downloads:
Toxicological Review of Acrylonitrile: in Support of Summary Information on the Integrated Risk Information System (IRIS) (Interagency Science Consultation Draft) (PDF, 767 pp, 3787 KB, about PDF)Selected sections and highlights of the External Peer Review Draft of Acrylonitrile (June 2011) (PDF, 6 pp, 52 KB, about PDF)
Charge to External Reviewers (Interagency Science Consultation Draft) (PDF, 4 pp, 36 KB, about PDF)
Interagency Science Consultation Comments and EPA's Response to Major Comments (PDF, 14 pp, 66 KB, about PDF)