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Nanosized Magnesium Oxide as Catalyst for the Rapid and Green Synthesis of Substituted 2-Amino-2-Chromenes
Citation:
KUMAR, D., V. REDDY, B. G. MISHRA, R. K. RANA, M. N. NADAGOUDA, AND R. S. VARMA. Nanosized Magnesium Oxide as Catalyst for the Rapid and Green Synthesis of Substituted 2-Amino-2-Chromenes. doi:10.1016/j.tet.20, L. Ghosez, Lin Guo-Qiang, T. Lectka, S.F. Martin, W.B. Motherwell, G. Pandey, R.J.K. Taylor, K. Tomioka (ed.), TETRAHEDRON. Elsevier Science Ltd, New York, NY, 63(15):3093-3097, (2007).
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publish information
Description:
A nanosized magnesium oxide catalyzed three-component condensation reaction of aldehyde, malononitrile and ¿-naphthol proceeded rapidly in water/PEG to afford corresponding 2-amino-2-chromenes in high yields at room temperature. The greener protocol was found to be fairly general and the catalyst was reused in subsequent reactions with consistent activity.
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NANOSIZED MAGNESIUM OXIDE AS CATALYST FOR THE RAPID AND GREEN SYNTHESIS OF SUBSTITUTED 2-AMINO-2-CHROMENES