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THE UTILIZATION OF THE NTP-HTS DATA IN CHEMICAL TOXICITY MODELING
Citation:
HAO, Z., A. M. RICHARD, I. RUSYN, AND A. TROPSHA. THE UTILIZATION OF THE NTP-HTS DATA IN CHEMICAL TOXICITY MODELING. Presented at 2007 Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.
Impact/Purpose:
To explore efficient approaches to assessing the toxicity of environmental chemicals, the NIEHS National Toxicology Program (NTP) recently initiated a High Throughput Screening (HTS) Project. To date, HTS results for a set of 1,408 compounds tested in 6 cell viability assays have been released via PubChem. This abstract explores herein the utility of the HTS data for predicting animal and human toxicity.
Description:
To explore efficient approaches to assessing the toxicity of environmental chemicals, the NIEHS National Toxicology Program (NTP) recently initiated a High Throughput Screening (HTS) Project. To date, HTS results for a set of 1,408 compounds tested in 6 cell viability assays have been released via PubChem. This abstract explores herein the utility of the HTS data for predicting animal and human toxicity.