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DETECTION AND QUANTIFICATION OF A THIO-ARSENOSUGAR IN MARINE MOLLUSKS BY IC-ICP-MS WITH AN EMPHASIS ON THE INTERATION OF ARSENOSUGARS WITH SULFIDE
Citation:
CONKLIN, S., P. A. CREED, AND JOHN T. CREED. DETECTION AND QUANTIFICATION OF A THIO-ARSENOSUGAR IN MARINE MOLLUSKS BY IC-ICP-MS WITH AN EMPHASIS ON THE INTERATION OF ARSENOSUGARS WITH SULFIDE. Presented at The 26th Ralph & Helen Oesper Banquet, Poster Session and Symposium, Cincinnati, OH, October 27 - 28, 2006.
Impact/Purpose:
To develop an arsenic speciation protocol for the analysis of dietary components and composite diets in order to provide a more accurate assessment of human exposure to arsenicals.
Description:
It has been found that strong-base extraction of marine mollusks liberates between 0.5-2 ppm sulfide along with arsenicals including arsenosugars. Results will be presented indicating that at a pH of 12, the sulfide is present as S2- and is unlikely to react with the arsenosugar oxide to produce the arsenosugar sulfide. However, acidification of these extracts converts S2- to H2S, which reacts with the arsenosugar oxide and accounts for the conversion to the arsenosugar sulfide observed upon extraction acidification. These results are significant in that extraction procedures which liberate both sulfide and arsenosugars from seafood samples are likely to produce enhanced arsenosugar sulfides if the pH is not adjusted basic to minimize the production of H2S.