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STRATEGIC BIOMONITORING INITIATIVES: MOVING THE SCIENCE FORWARD
Citation:
ANGERER, J., M. G. BIRD, T. A. BURKE, N. G. DOERRER, L. L. NEEDHAM, S. H. ROBISON, L. S. SHELDON, AND H. ZENICK. STRATEGIC BIOMONITORING INITIATIVES: MOVING THE SCIENCE FORWARD. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 93(1):3-10, (2006).
Impact/Purpose:
Objectives for this task include the following:
o Investigate the current research on biomarkers of exposure for humans (ILSI documents).
o Develop better measurement methods and procedures for collecting biomarkers of exposure in human research studies.
o Conduct advanced statistical analyses on existing urinary biomarker data generated from EPA funded studies.
o Identify and provide valuable data inputs for modelers in their toxicokinetic and exposure models.
o Use modeling tools to understand the exposures of humans to chemicals related to biomarkers of exposure.
o Form a collaborative partnership with CDC to develop analytical methods for chemicals used as biomarkers of exposure in humans.
o Develop statistical methods and models to assess human exposures to chemicals of concern.
Description:
Biomonitoring programs in the United States and Europe demonstrate the vast array of data that are publicly available for the evaluation of exposure trends, identification of susceptible populations, detection of emerging chemical risks, the conduct of epidemiology studies, and evaluation or risk reduction strategies.