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EXPOSURE ASSESSMENT FOR THE NATIONAL CHILDREN'S STUDY: INTEGRATING BIOMONITORING WITH ENVIRONMENTAL MEASURES AND QUESTIONNAIRE/DIARY/OBSERVATIONAL INFORMATION
Citation:
QUACKENBOSS, J. J., L. L. NEEDHAM, W. GALKE, S. VIET, AND B. OBRIEN. EXPOSURE ASSESSMENT FOR THE NATIONAL CHILDREN'S STUDY: INTEGRATING BIOMONITORING WITH ENVIRONMENTAL MEASURES AND QUESTIONNAIRE/DIARY/OBSERVATIONAL INFORMATION. Presented at International Council of Chemical Associations Workshop, Minneapolis, MN, July 26 - 27, 2006.
Impact/Purpose:
The overall goal of this research program is to identify those chemicals, pathways, and activities that represent the highest potential exposures to children and to determine the factors that influence these exposures. The following objectives will address this goal:
Revise and refine the existing research plan for children's exposure measurements research.
Collect measurement data on children's exposures.
Provide analytical support to children's pesticide exposure research.
Develop analytical methods for pesticides in duplicate diet food samples.
Develop and apply analytical methods for other chemicals including but not limited to brominated diphenyl ethers, phthalates, perfluorinated chemicals.
Evaluate the impact of chiral chemistry on the risk to children and exposure assessment.
Provide support to the National Children's Study.
Perform data analyses to fill critical data gaps.
Conduct analyses of dietary samples and refine the dietary model for the dietary exposure algorithm.
Description:
The National Children's Study (NCS) is proposed to be the largest and most ambitious study of the health and development of children ever to be undertaken in the United States. The Study is led by the U.S. Department of Health and Human Services - through the National Institutes of Health and the Centers for Disease Control and Prevention - and by the U.S. Environmental Protection Agency. The Study plans to enroll a representative sample of America's children (approximately 100,000 from more than 100 locations throughout the U.S.) and their families, and follow them longitudinally from either before conception or early in pregnancy until age 21 years to better understand the multiple factors which influence the physical and mental health and development of children.