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Exposures and Internal Doses of Trihalomethanes In Humans: Multi-Route Contributions From Drinking Water (Final)
Citation:
U.S. EPA. Exposures and Internal Doses of Trihalomethanes In Humans: Multi-Route Contributions From Drinking Water (Final). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-06/087, 2006.
Impact/Purpose:
Review Draft - by 2010, develop scientifically sound data and approaches to assess and manage risks to human health posed by exposure to specific regulated waterborne pathogens and chemicals, including those addressed by the Arsenic, M/DBP and Six-Year Review Rules.
Description:
The EPA has released a final report that presents and applies a method to estimate distributions of internal concentrations of trihalomethanes (THMs) in humans resulting from a residential drinking water exposure. The report presents simulations of oral, dermal and inhalation exposures and demonstrates the feasibility of linking the US EPA’s information Collection Rule database with other databases on external exposure factors and physiologically based pharmacokinetic modeling to refine population-based estimates of exposure.