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ENANTIOSELECTIVE CHRONIC TOXICITY OF FIPRONIL IN CERIODAPHNIA DUBIA
Citation:
WILSON, W. A., B. KONWICK, A. W. GARRISON, AND M. C. BLACK. ENANTIOSELECTIVE CHRONIC TOXICITY OF FIPRONIL IN CERIODAPHNIA DUBIA. Presented at Society of Environmental Toxicology and Chemistry Annual Meeting, Baltimore, MD, November 13 - 17, 2005.
Impact/Purpose:
To determine the environmental occurrences, fate, and effects of the enantiomers of selected chiral pesticides and other chiral pollutants.
Description:
Fipronil is released into the environment in a racemic (1:1) mixture of two mirror image isomers, called enantiomers. Although enantiomers undergo the same abiotic reactions and have identical physical properties, they may exhibit differing biological activity. Fipronil exhibited enantioselective toxicity in acute (48 h) toxicity tests with the aquatic crustacean Ceriodaphnia dubia, with the (+) enantiomer being up to three times more toxic.