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PARTNERING TO COLLECT IMPROVED HUMAN EXPOSURE MEASUREMENT DATA
Citation:
TULVE, N. S., A. F. VETTE, R. C. FORTMANN, D. BARR, K. D. BRADHAM, R. BROOK, J. M. BURKE, C. CAVE, E. A. COPPEDGE, D. L. COSTA, C. W. CROGHAN, K. EDGREN, A. FRASER, W. FRIEDMAN, S. L. HARPER, M. HEINDORF, R. HIGHSMITH, A. HILLIARD, D. JONES, A. B. LINDSTROM, P. J. LIOY, D. MARKER, L. J. MELNYK, S. MUKERJEE, L. NAEHER, L. M. NEAS, M. NISHIOKA, A. W. REA, L. S. SHELDON, J. SMITH, C. D. STEVENS, D. STOUT, S. VEIT, A. WHEELER, D. A. WHITAKER, R. W. WILLIAMS, AND J. ZHOU. PARTNERING TO COLLECT IMPROVED HUMAN EXPOSURE MEASUREMENT DATA. Presented at EPA Science Forum 2005, Washington, DC, May 16 - 18, 2005.
Impact/Purpose:
1. Identify and evaluate the factors that affect children's exposures as a function of age (for age bins proposed by EPA's Risk Assessment Forum).
2. Determine the impact of microenvironment and macroactivity on children's exposure to current-use pesticides and selected phthalates in residences.
3. Determine temporal variability of multimedia concentrations of selected pesticides and phthalates in the residences of very young children (0 to 3 years of age).
4. Perform aggregate exposure estimates for current-use pesticides (soon after application) and phthalates for very young children.
5. Evaluate the relationship between concentrations of biomarkers of exposure measured in urine and aggregate exposure estimates derived from diet and environmental measurements for pesticides and phthalates using the algorithms and approaches specified in the Draft Protocol for Measuring Children's Non-Occupational Exposure to Pesticides by all Relevant Pathways.
6. Evaluate and apportion exposure pathways for pesticides and phthalates.
7. Collect data for selected polybrominated diphenyl ethers (brominated flame retardants) and perfluorinated chemicals (PFOS and PFOA) in the diet and in environmental samples collected in the residences to assess spatial and temporal variability and the potential for children's exposure.
8. Evaluate the utility of the draft standardized protocol for performing exposure assessments for young children.
9. Develop critical inputs for the human exposure models (SHEDS, CARES, Lifeline, Calendex, and others).
10. Collect preliminary data on environmental concentrations of selected metals found in the outdoor residential environment.
11. Evaluate the utility of standardized data collection methods for future large scale studies.
Description:
Partnering allows complex environmental challenges to be efficiently addressed by leveraging resources and scientific expertise. The US Environmental Protection Agency's Office of Research and Development (ORD) routinely collaborates with other federal, state, and local government organizations, as well as academia and international groups, to address research questions related to pesticide and particulate matter exposures in non-occupational environments. This abstract highlights four collaborations undertaken since 2001: JAX, CCC, DEARS, and AHHS.