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ISSUES IN DERMAL EXPOSURE OF INFANTS
Citation:
COHEN-HUBAL, E. A. ISSUES IN DERMAL EXPOSURE OF INFANTS. JOURNAL OF CHILDREN'S HEALTH. Journal of Children's Health, Weston, MA, 2(3-4):253-265, (2005).
Impact/Purpose:
1. To identify those pesticides, pathways, and activities that represent the highest potential exposures to children;
2. To determine the factors that influence pesticide exposures to children;
3. To develop methods for measuring multimedia exposures to children, including methods that account for important activities that take place in home, school, and day care settings;
4. To generate data on multimedia pesticide concentrations, pesticide biomarkers, and exposure factors that can be used as inputs to aggregate exposure models for children.
Description:
Infants' dermal exposures to environmental contaminants are expected to be different and, in many cases, much higher than adults. Because of the potential importance of the dermal exposure route, there is currently a significant amount of work being conducted to reduce the uncertainties associated with assessing infants' dermal exposures. A conceptual model of dermal exposure is presented and issues associated with characterizing and assessing these exposures presented. Physiological and behavioral characteristics of infants that impact dermal exposure as well as exposure measurement and assessment approaches are discussed.