U.S. EPA. Surface Analysis Using Wipes for the Determination of Nitrogen Mustard Degradation Products by Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-11/143, 2011.
Wipe sampling can be performed quickly and easily when direct extraction is not always possible (e.g., walls, floors and furniture). As a result, wipe sampling is preferred for analysis without destruction of the tested surface. However, wipe sampling can remove analytes only from the surface of a material, which could result in lower recoveries and produce less reliable quantitative data from porous surfaces. It is therefore important to understand wipe efficiencies and the materials being wiped. This procedure assesses the recoveries from various porous and nonporous surfaces to determine the presence of nitrogen mustard degradation products.