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IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts (Public Comment and External Review Draft, 2021)
UPDATE: In June 2022, EPA released the final peer review report they received from ERG (a contractor to EPA) from the peer review they hosted on the review of the IRIS assessment of Perfluorobutanoic Acid (PFBA) and Related Salts. This meeting was held February 22-23, 2022.
Citation:
U.S. EPA. IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts (Public Comment and External Review Draft, 2021). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-20/424, 2021.
Impact/Purpose:
EPA is undertaking development of the Integrated Risk Information System (IRIS) health assessment for PFBA. The outcome of this project is an IRIS Toxicological Review and Executive Summary for PFBA that will be entered into the IRIS database.
Description:
The updated IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts draft was re-released for public comment and external peer review in October 2021. The IRIS assessment of PFBA will undergo an independent external scientific peer review managed by Eastern Research Group, Inc. (ERG), a contractor to EPA. Additional information about the peer review will be posted on the IRIS website. Additionally, the same peer review panel will conduct all five (5) PFAS IRIS assessments.
URLs/Downloads:
IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts (Public Comment and External Review Draft, Oct 2021) (PDF, 129 pp, 2921 KB, about PDF)IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts - Supplemental Information (Public Comment and External Review Draft, Oct 2021) (PDF, 90 pp, 1527 KB, about PDF)
IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Compound Ammonium Perfluorobutanoic Acid (Public Comment and External Review Draft, Aug 2021) (PDF, 130 pp, 3003 KB, about PDF)
IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Compound Ammonium Perfluorobutanoic Acid - Supplemental Information (Public Comment and External Review Draft, Aug 2021) (PDF, 91 pp, 1600 KB, about PDF)
Primary Literature Search References Sorted By Author (PFBA)
EPA-HQ-ORD-2020-0675
FR Notice: Oct 20, 2021 - Extension
FR Notice: Aug 23, 2021
FR Notice: Aug 23, 2021 (Panel)
PFBA Errata Sheet (PDF, 1 pp, 120 KB, about PDF)
PFBA Draft Charge to External Peer Reviewers (Public Comment and External Review Draft) (PDF, 6 pp, 207 KB, about PDF)
External Panel Peer Review of EPA's Draft "IRIS Toxicological Review of Perfluorobutanoic Acid (PFBA) and Related Salts" Final Peer Review Report (PDF, 107 pp, 1092 KB, about PDF)