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TRIHALOMETHANES IN DRINKING WATER AND SPONTANEOUS ABORTIONS
Impact/Purpose:
This epidemiology study was designed to evaluate if an association could be demonstrated between exposure to trihalomethanes and spontaneous abortions. The research is applicable to the Stage 2 DBP rule.
Description:
A limited number of epidemiological studies have evaluated the potential association between exposure to DBPs in drinking water and adverse reproductive outcomes. Reproductive effects that have been studied include, for example, spontaneous abortions, congenital defects, low birth weight, prematurity and small for gestational age. The risk estimates are highly uncertain due to differences in study design, characterization of exposures, and ascertainment of health effects. Toxicology studies of individual DBPs have demonstrated various adverse reproductive and developmental effects at the high experimental exposure levels used in these types of studies.