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EVALUATION OF THE POTENTIAL CARCINOGENICITY OF PHENACETIN
Citation:
EVALUATION OF THE POTENTIAL CARCINOGENICITY OF PHENACETIN. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-91/173.
Description:
Phenacetin is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). vidence on potential carcinogenicity from animal studies is "Sufficient," and the evidence from human studies is "Inadequate". he potency factor (F) for phenacetin is estimated to be 0.028 (mg/kg/day)-1 placing it in potency group 3 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). ombining the weight-of-evidence group and the potency group, phenacetin is assigned a "LOW" hazard ranking for the purposes of RQ adjustment.