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Comparative BioInformatics and Computational Toxicology
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Citation:
KNUDSEN, T. B. AND R. J. KAVLOCK. Comparative BioInformatics and Computational Toxicology. Chapter 12, Developmental Toxicology 3rd Edition. Taylor and Francis, Philadelphia, PA, 27:311-360, (2008).Description:
Reflecting the numerous changes in the field since the publication of the previous edition, this third edition of Developmental Toxicology focuses on the mechanisms of developmental toxicity and incorporates current technologies for testing in the risk assessment process.
Purpose/Objective:
It examines the role of computer modeling and bioinformatics, exploring how these areas can contribute to further understanding the overall process of development. The text also provides complete coverage of such topics as the role of apoptosis, cell-to-cell interactions, the importance of signal transduction, the use of stem cells and zebra fish, as well as whole animal toxicity testing systems
Record Details:
Record Type: DOCUMENT (BOOK CHAPTER)Start Date: 10/01/2008
Completion Date: 10/01/2008
Record Last Revised: 11/10/2008
Record Created: 07/25/2008
Record Released: 07/25/2008
OMB Category: Other
Record ID: 198217
Organization:
U.S. ENVIRONMENTAL PROTECTION AGENCYOFFICE OF RESEARCH AND DEVELOPMENT
NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY