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Use of Cell Viability Assay Data Improves the Prediction Accuracy of Conventional Quantitative Structure-Activity Relationship Models of Animal Carcinogenicity
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Citation:
Zhu, H., I. Rusyn, A. M. RICHARD, AND A. Tropsha. Use of Cell Viability Assay Data Improves the Prediction Accuracy of Conventional Quantitative Structure-Activity Relationship Models of Animal Carcinogenicity. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 116(4):506-513, (2008).Description:
Our study suggests that combining NTP-HTS profiles with conventional chemical descriptors could considerably improve the predictive power of computational approaches in toxicology.
Purpose/Objective:
Our study suggests that combining NTP-HTS profiles with conventional chemical descriptors could considerably improve the predictive power of computational approaches in toxicology.
Record Details:
Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)Start Date: 04/01/2008
Completion Date: 04/01/2008
Record Last Revised: 12/04/2008
Record Created: 07/03/2008
Record Released: 07/03/2008
OMB Category: Other
Record ID: 196089
Organization:
U.S. ENVIRONMENTAL PROTECTION AGENCYOFFICE OF RESEARCH AND DEVELOPMENT
NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY