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MECHANISTIC COMPUTATIONAL MODEL OF OVARIAN STEROIDOGENESIS TO PREDICT BIOCHEMICAL RESPONSES TO ENDOCRINE ACTIVE COMPOUNDS.
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Citation:
BREEN, M., D. L. VILLENEUVE, M. BREEN, G. T. ANKLEY, AND R. B. CONOLLY. MECHANISTIC COMPUTATIONAL MODEL OF OVARIAN STEROIDOGENESIS TO PREDICT BIOCHEMICAL RESPONSES TO ENDOCRINE ACTIVE COMPOUNDS. Dr. Gerald Saidel; Dr. Larry V. McIntire (ed.), Annals of Biomedical Engineering. Springer Netherlands, , Netherlands, 35(6):970-981, (2007).Description:
Our study demonstrates the feasibility of using the steroidogenesis model to predict T and E2 concentrations, in vitro, while reducing model complexity with a steady-state assumption.
Purpose/Objective:
Our study demonstrates the feasibility of using the steroidogenesis model to predict T and E2 concentrations, in vitro, while reducing model complexity with a steady-state assumption.
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MECHANISTIC COMPUTATIONAL MODEL OF OVARIAN STEROIDOGENESIS TO PREDICT BIOCHEMICAL RESPONSES TO ENDOCRINE ACTIVE COMPOUNDS.
Record Details:
Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)Start Date: 06/01/2007
Completion Date: 06/01/2007
Record Last Revised: 12/03/2008
Record Created: 05/16/2007
Record Released: 05/16/2007
OMB Category: Other
Record ID: 171103
Organization:
U.S. ENVIRONMENTAL PROTECTION AGENCYOFFICE OF RESEARCH AND DEVELOPMENT
NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY
IMMEDIATE OFFICE