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DEVELOPMENT AND USE OF PBPK MODELING AND THE IMPACT OF METABOLISM ON VARIABILITY IN DOSE METRICS FOR THE RISK ASSESSMENT OF METHYL TERTIARY BUTYL ETHER (MTBE)

Contact
JERRY N BLANCATO
phone: 919-541-2854
fax: 919-685-3334
email: blancato.jerry@epa.gov

Citation:

BLANCATO, J. N., M. V. EVANS, F. W. POWER, AND J. C. CALDWELL. DEVELOPMENT AND USE OF PBPK MODELING AND THE IMPACT OF METABOLISM ON VARIABILITY IN DOSE METRICS FOR THE RISK ASSESSMENT OF METHYL TERTIARY BUTYL ETHER (MTBE). Journal of Environmental Science and Health. Marcel Dekker Incorporated, New York, NY, 1:29-51, (2007).

Description:

Report improvements to existing rodent and human PBPK models, and compare model predictions with available experimental data.

Purpose/Objective:

Report improvements to existing rodent and human PBPK models, and compare model predictions with available experimental data.

URLs/Downloads:

Development and Use of PBPK Modeling and the Impact of ....  Exit EPA's Web Site

Record Details:

Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)
Start Date: 11/01/2007
Completion Date: 11/01/2007
Record Last Revised: 12/03/2008
Record Created: 02/06/2007
Record Released: 02/06/2007
OMB Category: Other
Record ID: 163908

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF RESEARCH AND DEVELOPMENT
NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY
IMMEDIATE OFFICE
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