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Exposure Research

Records 1 to 54 of 54
2014
Tan, C., D. Chang, M. Phillips, S. Edwards, C. Grulke, Rocky Goldsmith, J. Sobus, R. Conolly, R. Tornero-Velez, AND C. Dary. Biomarkers in Computational Toxicology. Chapter 63, Biomarkers in Toxicology. Elsevier, Shannon, Ireland, , 1039-1055, (2014).
Goldsmith, Rocky, C. Grulke, R. Brooks, T. Transue, C. Tan, A. Frame, P. Egeghy, R. Edwards, D. Chang, R. Tornero-Velez, K. Isaacs, A. Wang, J. Johnson, K. Holm, M. Reich, J. Mitchell, D. Vallero, L. Phillips, M. Phillips, J. Wambaugh, R. Judson, T. Buckley, AND C. Dary. Development of a Consumer Product Ingredient Database for Chemical ExposureScreening and Prioritization. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 65:269-279, (2014).
2013
Goldsmith, Rocky, C. Grulke, D. Chang, C. Tan, R. Brooks, C. Dary, AND D. Vallero. Personal Chemical Exposure informatics. Chapter 1, McGraw-Hill Handbook of Science & Technology. McGraw-Hill Companies, New York, NY, , 1-9, (2014).
2012
TAN, Y., C. C. DARY, D. CHANG, E. M. ULRICH, J. M. VAN EMON, J. XUE, J. D. PLEIL, J. F. KENNEKE, J. SOBUS, L. S. SHELDON, M. K. MORGAN, M. GOLDSMITH, R. TORNERO-VELEZ, R. HIGHSMITH, R. C. FORTMANN, T. W. COLLETTE, AND V. G. ZARTARIAN. Biomonitoring - An Exposure Science Tool for Exposure and Risk Assessment. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-12/039 (NTIS PB2012-112321), 2012.
KNAAK, J. B., Y. TAN, AND C. C. DARY. Chapter 5. Pesticide Regulations: Exposure-dose modeling from FIFRA to FQPA. 1stChapter 5, E. Hodgson (ed.), Toxicology and Human Environments. Elsevier Ltd., Great Britain, Uk, 112:117-162, (2012).
TAN, Y., R. CONOLLY, D. CHANG, R. TORNERO-VELEZ, M. GOLDSMITH, S. PETERSON, AND C. C. DARY. Computational Toxicology: Application in Environmental Chemicals. Chapter 2, Brad Reisfeld and Arthur N. Mayeno (ed.), Computational Toxicology: Volume 1, Methods in Molecular Biology. Springer Science + Business Media, New York, NY, 929:1-11, (2012).
Chang, D., Rocky Goldsmith, R. Tornero-Velez, C. Tan, C. Grulke, E. Ulrich, A. Lindstrom, M. Pasquinelli, J. Rabinowitz, AND C. Dary. In Silico Strategies for Modeling Stereoselective Metabolism of Pyrethroids. Chapter 16, Parameters for Pesticide QSAR and PBPK Models for Human Risk Assessment. American Chemical Society, Washington, DC, 1099:245-269, (2012).
GOLDSMITH, M., S. PETERSON, D. CHANG, T. R. Transue, R. TORNERO-VELEZ, Y. TAN, AND C. C. DARY. Informing Mechanistic Toxicology with Computational Molecular Models. Chapter 7, B Reisfeld, A Mayeno (ed.), Computational Toxicology - Volume I, Methods in Molecular Biology. Springer Science + Business Media, New York, NY, 929(2012):139-165, (2012).
Goldsmith, Rocky, J. Johnson, D. Chang, R. Tornero-Velez, J. Knaak, AND C. Dary. Parameters for Pesticide QSAR and PBPK/PD Models to inform Human Risk Assessments. Chapter 1, James B. Knaak, Charles Timchalk, Rogelio Tornero-Velez (ed.), Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment. American Chemical Society, Washington, DC, 1099:1-15, (2012).
KNAAK, J. B., C. C. DARY, X. Zhang, R. W. Gerlach, R. TORNERO-VELEZ, D. CHANG, M. GOLDSMITH, AND J. N. BLANCATO. Parameters for Pyrethroid Insecticide QSAR and PBPK/PD Models for Human Risk Assessment . Chapter INT, Springer, New York, NY, 219:1-114, (2012).
2010
Zhang, X., J. B. KNAAK, R. TORNERO-VELEZ, J. N. BLANCATO, AND C. C. DARY. Application of Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling in Cumulative Risk Assessment for <I>N</I>-Methyl Carbamate Insecticides. ThirdChapter 73, Robert Krieger (ed.), Handbook of Pesticide Toxicology. Elsevier Ltd, Oxford, Uk, 2:1591-1605, (2010).
VALLERO, D. A., S. ISUKAPALLI, V. G. ZARTARIAN, T. R. MCCURDY, T. MCKONE, P. Georgopoulos, AND C. C. DARY. Modeling and Predicting Pesticide Exposures. 3Chapter 44, Robert Krieger (ed.), Hayes Handbook of Pesticide Toxicology. Elsevier Science, New York, NY, 1:995-1020, (2010).
GOLDSMITH, M., T. R. Transue, D. CHANG, R. TORNERO-VELEZ, AND C. C. DARY. PAVA: Physiological and Anatomical Visual Analytics for Mapping of Tissue-Specific Concentration and Time-Course Data. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. Springer, New York, NY, 37(3):277-287, (2010).
2009
TAN, C., E. J. WEBER, J. F. KENNEKE, M. K. MORGAN, D. CHANG, M. GOLDSMITH, R. TORNERO-VELEZ, AND C. C. DARY. Computational Approaches and Tools for Exposure Prioritization and Biomonitoring Data Interpretation. Presented at Computational Toxicology Board of Scientific Counselors Review, RTP, NC, September 29 - 30, 2009.
2007
XIAOFEI, Z., M. S. OKINO, J. B. KNAAK, A. M. TSANG, F. W. POWER, J. XUE, L. S. HARRISON, C. B. THOMPSON, AND C. C. DARY. A PHYSIOLOGICALLY BASED PHARMACOKINETIC/PHARMACODYNAMIC (PBPK/PD) MODEL FOR ESTIMATION OF CUMULATIVE RISK FROM EXPOSURE TO THREE N-METHYL CARBAMATES: CARBARYL, ALDICARB, AND CARBOFURAN. Presented at 2007 Society of Toxicology Annual Meeting, Charlotte , NC, March 25 - 29, 2007.
BLANCATO, J. N., F. W. POWER, A. RUIZ, A. TSANG, M. S. OKINO, J. C. JOHNSON, C. C. DARY, N. HERAVI, R. N. BROWN, AND L. S. SHELDON. EXPOSURE RELATED DOSE ESTIMATING MODEL (ERDEM). U.S. Environmental Protection Agency, Washington, DC, EPA/600/C-07/010, 2007.
POWER, F. W., C. C. DARY, J. B. KNAAK, R. TORNERO-VELEZ, AND J. N. BLANCATO. MALATHION EXPOSURE DURING LICE TREATMENT: USE OF EXPOSURE RELATED DOSE ESTIMATING MODEL (ERDEM) AND FACTORS RELATING TO THE EVALUATION OF RISK. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-07/023 (NTIS PB2007-106971), 2007.
TORNERO-VELEZ, R., E. SCOLLON, J. M. STARR, M. F. HUGHES, M. J. DEVITO, AND C. C. DARY. PHARMACOKINETIC/PHARMACODYNAMIC MODELING OF PERMETHRIN IN THE RAT. Presented at 2007 Society of Toxicology Annual Meeting, Charlotte, NC, March 25 - 29, 2007.
2006
CHANG, D., T. L. WHITEHEAD, M. S. OKINO, C. S. MAZUR, J. F. KENNEKE, R. TORNERO-VELEZ, J. C. JOHNSON, AND C. C. DARY. AN IN SILICO INVESTIGATION OF THE ENANTIOSELECTIVE METABOLISM RATES OF TRIAZOLE FUGICIDES. Presented at 14th North American International Society for the Study of Xenobiotics Meeting, Rio Grande, PUERTO RICO, October 22 - 26, 2006.
ZHANG, X., A. M. TSANG, M. S. OKINO, F. W. POWER, J. B. KNAAK, AND C. C. DARY. CONSTRUCTION OF A PHYSIOLOGICALLY BASED PHARMACOKINETIC/PHARMACODYNAMIC (PBPK/PD) MODEL FOR CARBOFURAN USING THE EXPOSURE RELATED DOSE ESTIMATING MODEL (ERDEM). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-06/135 (NTIS PB2007-100680), 2006.
TORNERO-VELEZ, R., J. XUE, E. SCOLLON, J. M. STARR, P. P. EGEGHY, D. B. BARR, M. J. DEVITO, AND C. C. DARY. DIETARY EXPOSURE TO PYRETHROIDS IN THE U.S POPULATION. Presented at ISEA/ISEE 2006, Paris, FRANCE, September 02 - 06, 2006.
CHANG, D., M. S. OKINO, FRED W. POWER, R. TORNERO-VELEZ, J. F. KENNEKE, CHRIS S. MAZUR, C. C. DARY, AND TIM W. COLLETTE. ESTIMATION OF CHEMICAL SPECIFIC PARAMETERS WITHIN PHYSIOLOGICALLY BASED PHARMACOKINETIC/PHARMACODYNAMIC MODELS. Presented at EPA Science Forum 2006, Washington, DC, May 16 - 18, 2006.
BLANCATO, J. N., F. W. POWER, R. N. BROWN, AND C. C. DARY. EXPOSURE RELATED DOSE ESTIMATING MODEL ( ERDEM ) A PHYSIOLOGICALLY-BASED PHARMACOKINETIC AND PHARMACODYNAMIC ( PBPK/PD ) MODEL FOR ASSESSING HUMAN EXPOSURE AND RISK. U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-06/061 (NTIS PB2006-114712), 2006.
CHANG, D., P. P. EGEGHY, J. B. KNAAK, R. TORNERO-VELEZ, M. S. OKINO, F. W. POWER, M. DELLARCO, C. S. MAZUR, J. F. KENNEKE, AND C. C. DARY. INFLUENCE OF MATRIX FORMULATION ON DERMAL PERCUTANEOUS ABSORPTION OF TRIAZOLE FUNGICIDES USING QSAR AND PBPK / PD MODELS. Presented at ISEA/ISEE 2006 , Paris, FRANCE, September 02 - 06, 2006.
OKINO, M. S., C. B. THOMPSON, F. W. POWER, R. TORNERO-VELEZ, A. TSANG, J. N. BLANCATO, AND C. C. DARY. URINARY BIOMARKER INTERPRETATION USING PHARMACOKINETIC MODELS. Presented at International Council of Chemistry Associations Workshop, Minneapolis, MN, July 26 - 27, 2006.
ZHANG, X., M. S. OKINO, FRED W. POWER, J. B. KNAAK, A. M. TSANG, L. S. HARRISON, A. O. RUIZ, C. B. THOMPSON, AND C. C. DARY. USE OF EXPOSURE RELATED DOSE ESTIMATING MODEL ( ERDEM ) TO CONSTRUCT A PBPK /MODEL FOR CARBOFURAN WITH THE REPORTED EXPERIMENTAL DATA IN THE RAT. Presented at Society of Toxicology, San Diego, CA, March 05 - 09, 2006.
2005
KNAAK, J. B., D. CHANG, C. C. DARY, R. TORNERO-VELEZ, M. S. OKINO, AND FRED W. POWER. ESTIMATION OF ADIPOSE TISSUE; BLOOD PARTITION COEFFICIENTS OF CARBAMATES AND ORGANOPHOSPHORUS PESTICIDES USING RELATIVE LIPID CONTENT AND LOGP AS THE MECHANISTIC DETERMINANTS. Presented at American Chemical Society Meeting and Exposition, Washington, DC, August 27 - September 01, 2005.
Nocerino, J M., B A. Schumacher, AND C C. Dary. ROLE OF LABORATORY SAMPLING DEVICES AND LABORATORY SUBSAMPLING METHODS IN OPTIMIZING REPRESENTATIVENESS STRATEGIES. ENVIRONMENTAL FORENSICS. Taylor & Francis, Inc., Philadelphia, PA, 6:35-44, (2005).
OKINO, M. S., W. CHIU, M. V. EVANS, F. W. POWER, J. C. LIPSCOMB, R. TORNERO-VELEZ, C. C. DARY, J. N. BLANCATO, C. CHEN, AND L. S. BIRNBAUM. SUITABILITY OF USING IN VITRO AND COMPUTATIONALLY ESTIMATED PARAMETERS IN SIMPLIFIED PHARMACOKINETIC MODELS. Presented at North American ISSX Meeting , Maui, HI, October 23 - 27, 2005.
OKINO, M. S., F. W. POWER, J. B. KNAAK, R. TORNERO-VELEZ, C. LUNCHICK, A. LOWIT, J. N. BLANCATO, AND C. C. DARY. USE OF A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO ESTIMATE ABSORBED CARBARYL DOSE IN CHILDREN AFTER TURF APPLICATION. Presented at Socieity of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
POWER, F. W., J. B. KNAAK, M. S. OKINO, R. TORNERO-VELEZ, J. N. BLANCATO, AND C. C. DARY. USE OF EXPOSURE-RELATED DOSE ESTIMATING MODEL (ERDEM) FOR ASSESSMENT OF AGGREGATE EXPOSURE OF INFANT AND CHILDREN TO N-METHYL CARBAMATE INSECTICIDES. Presented at Society of Toxicology Annual Meeting, New Orleans, LA, March 06 - 10, 2005.
TORNERO-VELEZ, R., N. S. TULVE, M. S. OKINO, AND C. C. DARY. USE OF PBPK MODELING TO ASSESS CYPERMETHRIN EXPOSURE IN YOUNG AFTER A RESIDENTIAL APPLICATION. Presented at International Society of Exposure Analysis Conference, Tucson, AZ, October 30 - November 03, 2005.
OKINO, M. S., G. CHAPA, K. W. THOMAS, G. L. ROBERTSON, C. B. THOMPSON, A. TSANG, FRED W. POWER, J. B. KNAAK, AND C. C. DARY. USE OF PHARMACOKINETIC MODELS TO ASSESS OCCUPATIONAL AND RESIDENTIAL PESTICIDE EXPOSURE. Presented at International Society for Exposure Analysis Conference, Tucson, AZ, October 30 - November 03, 2005.
2004
Ruiz, A., A. Tsang, J. Licitra, F W. Power, J N. Blancato, AND C C. Dary. A COMPREHENSIVE APPROACH FOR PHYSIOLOGICALLY BASED PHARMACOKINETIC (PBPK) MODELS USING THE EXPOSURE RELATED DOSE ESTIMATING MODEL (ERDEM) SYSTEM. Presented at 43rd Annual Meeting of the Society of Toxicology, Baltimore, MD, March 21-25, 2004.
TORNERO-VELEZ, R, C C. Dary, M Dellarco, AND J Blancato. A PBPK MODEL OF PYRETHROID PESTICIDES FOR APPLICATION IN RISK ASSESSMENT. Presented at Exposure Assessment in a Changing Environment, Utrecht, The Netherlands, June 16-18, 2004.
Dary, C C., M Dellarco, J N. Blancato, AND R. TORNERO-VELEZ. A PRELIMINARY PBPK MODEL OF PYRETHROID PESTICIDES FOR APPLICATION IN ENVIRONMENTAL RISK ASSESSMENT. Presented at X2004 - Exposure Assessment in a Changing Environment, Utrecht, The Netherlands, June 16-18, 2004.
TORNERO-VELEZ, R, W. Longest, S. Harper, C C. Dary, AND J Blancato. ADVANCED COMPUTATIONAL METHODS IN DOSE MODELING: APPLICATION OF COMPUTATIONAL BIOPHYSICAL TRANSPORT, COMPUTATIONAL CHEMISTRY, AND COMPUTATIONAL BIOLOGY. Presented at EPA Science Forum 2004, Washington, DC, June 1-3, 2004.
Blancato, J, C C. Dary, M S. Okino, F W. Power, A. Ruiz, AND R. TORNERO-VELEZ. APPLICATION OF ERDEM IN RISK ASSESSMENT: HEALTH EFFECTS DIVISION'S RISK ASSESSOR TRAINING AND CERTIFICATION PROGRAM. Presented at Health Effects Division's Risk Assessor Training and Certification Program, Washington, DC, August 11-12, 2004.
Ruiz, A., A. Tsang, F W. Power, J. Licitra, J N. Blancato, C C. Dary, AND M V. Evans. COMPREHENSIVE PBPK MODELING APPROACH USING THE EXPOSURE RELATED DOSE ESTIMATING MODEL (ERDEM). Presented at Society of Toxicology, Baltimore, MD, March 21-25, 2004.
Lowit, A., C C. Dary, F W. Power, J Blancato, R. W. Setzer, R. Conolly, AND M. Seaton. PHYSIOLOGICALLY-BASED PHARMACOKINETIC/PHARMACODYNAMIC MODELING AND CUMULATIVE RISK ASSESSMENT: CASE STUDY FOR THE N-METHYL CARBAMATE PESTICIDES. Presented at EPA Science Forum 2004, Washington, DC, June 1-3, 2004.
Lowit, A., C C. Dary, F W. Power, J Blancato, R. W. Setzer, R. Conolly, AND M. Seaton. PHYSIOLOGICALLY-BASED PHARMACOKINETICS/PHARMACODYNAMIC MODELING AND CUMULATIVE RISK ASSESSMENT: CASE STUDY FOR THE N-METHYL CARBMATE PESTICIDES. Presented at EPA Science Forum 2004, Washington, DC, June 1-3, 2004.
TORNERO-VELEZ, R, H P. Nichols, M V. Evans, M J. DeVito, C C. Dary, M Dellarco, AND J Blancato. TOWARDS A GENERIC PBPK MODEL OF PYRETHROID PESTICIDES: MODELING DELTAMETHRIN AND PERMETHRIN IN THE RAT. Presented at Society of Toxicology, Baltimore, MD, March 21-25, 2004.
2003
TORNERO-VELEZ, R, C C. Dary, J. B. Knaak, F W. Power, AND M Dellarco. A COMPARATIVE INVESTIGATION OF THE INFLUENCE OF DERMAL APPENDAGES (HAIR FOLLICLES) ON THE PERCUTANEOUS ABSORPTION OF ORGANOPHOSPHORUS (OP) INSECTICIDES USING QSAR AND PBPK/PD MODELS FOR HUMAN RISK ASSESSMENT. Presented at International Society of Exposure Analysis, Stresa, Italy, September 21-25, 2003.
Knaak, J. B., R TORNERO-VELEZ, F W. Power, J N. Blancato, AND C C. Dary. BETTER EXPOSURE-DOSE MODELS FOR PESTICIDES. Presented at Science Forum 2003, Washington, DC, May 5-7, 2003.
Knaak, J. B., F W. Power, J N. Blancato, AND C C. Dary. THE IMPORTANCE OF OBTAINING INFORMATION ON THE SPECIFIC CONTENT OF TISSUE ENZYMES METABOLIZING ORGANOPHOSPHORUS PESTICIDES, PRIOR TO DETERMINE VMAX, KM VALUES FOR USE IN PBPK MODELS. Presented at Science Forum 2003, Washington, DC, May 5-7, 2003.
Knaak, J. B., F W. Power, J N. Blancato, AND C C. Dary. THE IMPORTANCE OF OBTAINING INFORMATION ON THE SPECIFIC CONTENT OF TISSUE ENZYMES METABOLIZING ORGANOPHOSPHORUS PESTICIDES, PRIOR TO DETERMINING VMAX, KM VALUES FOR USE IN PBPK MODELS. Presented at American Chemical Society, New Orleans, LA, March 23-27, 2003.
2002
Dary, C C., E J. Furtaw Jr., F W. Power, AND J N. Blancato. PHYSIOLOGICALLY-BASED PHARMACOKINETIC AND PHARMACODYNAMIC (PBPK/PD) MODEL FOR PREDICTING THE DERMAL DOSE AND DISPOSITION OF ORGANOPHOSPHORUS INSECTICIDES. Presented at Society for Risk Analysis Meeting, New Orleans, LA, December 8-11, 2002.
Dary, C C., J. B. Knaak, F W. Power, C. B. Thompson, AND J N. Blancato. PREDICTIVE ORGANOPHOSPHORUS (OP) PESTICIDE QSARS AND PBPK/PD MODELS FOR RISK ASSESSMENT OF SUSCEPTIBLE SUB-POPULATIONS. Presented at Society of Toxicology, Las Vegas, NV, September 26-27, 2002.
Knaak, J. B., C C. Dary, G. T. Patterson, AND J N. Blancato. WORKER HAZARD POSED BY REENTRY INTO PESTICIDE-TREATED FOLIAGE: REASSESSMENT OF REENTRY LEVELS/INTERVALS USING FOLIAR RESIDUE TRANSFER - PERCUTANEOUS ABSORPTION PBPK/PD MODELS, WITH EMPHASIS ON ISOFENPHOS AND PARATHION. Chapter 13, Human and Ecological Risk Assessment: Theory and Practice. John Wiley & Sons Incorporated, New York, NY, , 673-731, (2002).
2001
2000
Dary, C C., Z. Mohammed, AND M. A. Saleh. CHEMOMORPHIC ANALYSIS OF MALATHION IN SKIN LAYERS: IMPLICATIONS FOR THE USE OF DERMATOPHARMACOKINETIC (DPK) TAPE STRIPPING IN EXPOSURE ASSESSMENT TO PESTICIDES. Presented at Annual Meeting of Society of Toxicology, Philadelphia, PA, March 19-23, 2000.
Blancato, J N., J. B. Knaak, F. W. Power, AND C C. Dary. USE OF PBPK MODELS FOR ASSESSING ABSORBED DOSE AND CHE INHIBITION FROM AGGREGATE EXPOSURE OF INFANTS AND CHILDREN TO ORGANOPHOSPHORUS INSECTICIDES. Presented at ISEA 2000 Exposure Analysis in the 21st Century: Integrating Science, Policy and Quality of Life, Monterey Peninsula, CA, October 24-27, 2000.
Knaak, J. B., C C. Dary, G. T. Patterson, AND J N. Blancato. USE OF PBPK/PD MODELS AND FOLIAR TRANSFER COEFFICIENTS IN ASSESSING REENTRY INTO PESTICIDE TREATED CITRUS AND TURF. Presented at Annual Meeting of Society of Toxicology, Philadelphia, PA, March 19-23, 2000.
1999
Furtaw Jr., E J., C C. Dary, M. Dellarco, AND C G. Saint. AN EQUILIBRIUM-APPROACH MODEL FOR SIMULATING CONTAMINANT TRANSFER BETWEEN SURFACES AND SKIN IN SUPPORT OF FQPA. Presented at Society for Risk Analysis, 1999 Annual Meeting, Atlanta, GA, December 5-8, 1999.


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