Jump to main content or area navigation.

Contact Us

Computational Toxicology Research

Key Links
CompTox Home Basic Information Organization EPA Exposure Research Research Projects Chemical Databases ToxCast Stakeholder Events EPA Chemical Safety Research Research Publications Scientific Reviews Communities of Practice ToxCast Data Challenges Staff Profiles CompTox Partners Jobs and Opportunities
Records 1 to 19 of 19 for search term "vEmbryo"
2014
Leist, M., N. Hasiwa, C. Rovida, M. Daneshian, D. Basketter, I. Kimber, H. Clewell, T. Gocht, A. Goldberg, F. Busquet, A. Rossi, M. Schwarz, M. Stephens, R. Taalman, T. Knudsen, J. McKim, G. Harris, D. Pamies, AND T. Hartung. Consensus report on the future of animal-free systemic toxicity testing. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 31(3):341-356, (2014).
2012
BASKETTER, D. A., H. J. CLEWELL, I. KIMBER, A. ROSSI, B. BLAAUBOER, R. BURRIER, M. DANESHIAN, C. ESKES, A. GOLDBERG, N. HASIWA, S. HOFFMANN, J. JAWORSKA, T. B. KNUDSEN, R. LANDSIEDEL, M. LEIST, P. LOCKE, G. MAXWELL, J. MCKIM, E. A. MCVEY, G. OUEDRAOGO, G. PATLEWICZ, O. PELKONEN, E. ROGGEN, C. ROVIDA, I. RUHDEL, M. SCHWARZ, A. SCHEPKY, G. SCHOETERS, N. SKINNER, K. TRENTZ, M. TURNER, P. VANPARYS, J. YAGER, J. ZURLO, AND T. HARTUNG. A Roadmap for the Development of Alternative (Non-Animal) Methods for Systemic Toxicity Testing. SONJA von AULOCK, Editor in chief (ed.), ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 1(29):1-91, (2012).
KNUDSEN, T. B. AND N. C. KLEINSTREUER. Disruption of Embryonic Vascular Development in Predictive Toxicology. Anthony M. DeLise (Guest Editor) (ed.), Birth Defects Research, Part C: Embryo Today: Reviews. John Wiley & Sons, Ltd., Indianapolis, IN, 93(4):312-323, (2011).
MARTIN, M. T., T. B. KNUDSEN, R. JUDSON, R. J. KAVLOCK, AND D. J. DIX. Economic benefits of using adaptive predictive models of reproductive toxicity in the context of a tiered testing program . Stephen A. Krawetz (Editor-in-Chief) (ed.), Systems Biology in Reproductive Medicine. Informa Healthcare USA, New York, NY, 58(1):3-9, (2012).
KLEINSTREUER, N., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, K. B. PAUL, D. REIF, K. M. CROFTON, K. HAMILTON, R. HUNTER, I. A. SHAH, AND R. JUDSON. In vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, Epub(Advance Access):1-44, (2012).
PADILLA, S. J., D. CORUM, B. K. PADNOS, D. L. HUNTER, A. BEAM, K. A. HOUCK, N. SIPES, N. KLEINSTREUER, T. B. KNUDSEN, D. J. DIX, AND D. M. REIF. Zebrafish Developmental Screening of the ToxCast™ Phase I Chemical Library . REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 33(2):174-187, (2012).
2011
KNUDSEN, T. B., K. A. HOUCK, N. SIPES, A. V. SINGH, R. JUDSON, M. T. MARTIN, A. WEISSMAN, N. KLEINSTREUER, H. M. MORTENSEN, D. REIF, J. R. RABINOWITZ, R. W. SETZER, A. M. RICHARD, D. J. DIX, AND R. J. KAVLOCK. Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 282(1-2):1-15, (2011).
KNUDSEN, T. B., R. J. KAVLOCK, G. P. DASTON, D. B. STEDMAN, M. HIXON, AND J. KIM. Developmental toxicity testing for safety assessment: new approaches and technologies. BIRTH DEFECTS RESEARCH PART B: DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY. John Wiley & Sons, Inc, Hoboken, NJ, 92(5):413-420, (2011).
GREEN, M. L., A. V. SINGH, L. RUEST, MICHELE M. PISANO, R. A. PROUGH, AND T. B. KNUDSEN. Differential programming of p53-deficient embryonic cells during rotenone block. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 290(1):31-41, (2011).
KLEINSTREUER, N. C., R. S. JUDSON, D. M. REIF, N. S. SIPES, A. V. SINGH, K. J. CHANDLER, R. DEWOSKIN, D. J. DIX, R. J. KAVLOCK, AND T. B. KNUDSEN. Environmental Impact on Vascular Development Predicted by High Throughput Screening. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(11):1596-1603, (2011).
KLEINSTREUER, N. C., A. M. SMITH, P. R. WEST, K. CONARD, B. FONTAINE, A. M. WEIR-HAUPTMAN, J. PALMER, T. B. KNUDSEN, D. J. DIX, E. L. DONLEY, AND G. G. CEZAR. Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics . TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier Science Inc., Burlington, MA, Online:1-10, (2011).
MARTIN, M. T., T. B. KNUDSEN, D. REIF, K. A. HOUCK, R. JUDSON, R. J. KAVLOCK, AND D. J. DIX. Predictive Model of Rat Reproductive Toxicity from ToxCast High Throughput Screening. BIOLOGY OF REPRODUCTION. Society for the Study of Reproduction, 85(2):327-339, (2011).
SIPES, N. S., M. T. MARTIN, D. M. REIF, N. C. KLEINSTREUER, R. S. JUDSON, A. V. SINGH, K. J. CHANDLER, D. J. DIX, R. J. KAVLOCK, AND T. B. KNUDSEN. Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 124(1):109-127, (2011).
SIPES, N. S., S. J. PADILLA, AND T. B. KNUDSEN. Zebrafish – As an Integrative Model for Twenty-first Century Toxicity Testing. Birth Defects Research, Part C: Embryo Today: Reviews. Wiley Liss, New York, NY, 93(3):256-267, (2011).
2010
KAVLOCK, R. J. AND D. J. DIX. Computational Toxicology as Implemented by the U.S. EPA: Providing High Throughput Decision Support Tools for Screening and Assessing Chemical Exposure, Hazard and Risk. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 1(2-4):197-217, (2010).
Ema, M., R. Ise, H. Kato, S. Oneda, A. Hirose, M. Hirata-Koizumi, A. V. SINGH, T. B. KNUDSEN, AND T. Ihara. Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 29(1):49-56, (2010).
KNUDSEN, T. B. AND D. M. KOCHHAR. The Hemimelic extra toes mouse mutant: Historical perspective on unraveling mechanisms of dysmorphogenesis. Birth Defects Research, Part C: Embryo Today: Reviews. John Wiley & Sons, Ltd., Indianapolis, IN, 90(2):155-162, (2010).
SHAH, I. A. AND J. F. WAMBAUGH. Virtual Tissues in Toxicology. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 13(2-4):314-328, (2010).
2009
KNUDSEN, T. B., M. T. MARTIN, R. J. KAVLOCK, R. JUDSON, D. J. DIX, AND A. V. SINGH. Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA’s ToxRefDB. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 28(2):209-19, (2009).


Jump to main content.