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Records 1 to 14 of 14 for search term "uncertainty"
2014
Slob, W. AND W. Setzer. Shape and Steepness of Toxicological Dose-Response Relationships of Continuous Endpoints. CRITICAL REVIEWS IN TOXICOLOGY. CRC Press LLC, Boca Raton, FL, 44(3):270-297, (2014).
2013
WAMBAUGH, J. F., R. W. SETZER, D. REIF, S. GANGWAL, J. MITCHELLBLACKWOOD, J. A. ARNOT, O. JOLIET, A. FRAME, J. R. RABINOWITZ, T. B. KNUDSEN, R. S. JUDSON, P. P. EGEGHY, D. A. VALLERO, AND E. A. COHEN HUBAL. High-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project . Jerald Schnoor (ed.), ENVIRONMENTAL SCIENCE AND TECHNOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 47(15):8479-8488, (2013).
2011
JUDSON, R., R. J. KAVLOCK, R. W. SETZER, E. A. COHEN-HUBAL, M. T. MARTIN, T. B. KNUDSEN, K. A. HOUCK, R. S. THOMAS, B. A. WETMORE, AND D. J. DIX. Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 24(4):451-462, (2011).
MORTENSEN, H. M. AND S. EULING. Integrating mechanistic and polymorphism data to characterize human genetic susceptibility for environmental chemical risk assessment in the 21st century. TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier BV, AMSTERDAM, Netherlands, (Online):1-10, (2011).
2010
BENFORD, D., M. DINOVI, AND R. W. SETZER. Application of the Margin of Exposure (MoE) Approach to Substances in Food that are Genotoxic and Carcinogenic Example: Benzo[a]pyrene and polycyclic aromatic hydrocarbons. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 48(1):S2-S24, (2010).
Xu, Y., E. A. COHEN-HUBAL, AND J. C. Little. Predicting Residential Exposure to Phthalate Plasticizer Emitted from Vinyl Flooring: Sensitivity, Uncertainty, and Implications for Biomonitoring. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(2):253-8, (2010).
WAMBAUGH, J. F. AND I. A. SHAH. Simulating Microdosimetry in a Virtual Hepatic Lobule. PLoS Computational Biology. Public Library of Science, San Francisco, CA, 6(4):1-16, (2010).
SOETAERT, K., T. PETZOLDT, AND R. W. SETZER. Solving Differential Equations in R: Package deSolve. Journal of Statistical Software. American Statistical Association, Alexandria, VA, 33(9):1-25, (2010).
2009
Lou, I., J. F. WAMBAUGH, C. LAU, R. HANSON, A. B. LINDSTROM, M. STRYNAR, R. ZEHR, R. W. SETZER, AND H. A. BARTON. Modeling Single and Repeated Dose Pharmacokinetics of PFOA in Mice (J). TOXICOLOGICAL SCIENCES. Society of Toxicology, 107(2):331-41, (2009).
RODRIGUEZ, C. E., R. W. SETZER, AND H. A. BARTON. Pharmacokinetic Modeling of Perfluorooctanoic Acid During Gestation and Lactation in the Mouse. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 3-4:373-86, (2009).
2008
WAMBAUGH, J. F., H. A. BARTON, AND R. W. SETZER. Comparing models for perfluorooctanoic acid pharmacokinetics using Bayesian analysis. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. Springer, New York, NY, 35(6):683-712, (2008).
Yoon, M. AND H. A. BARTON. Predicting Maternal Rat and Pup Exposures: How Different Are They? TOXICOLOGICAL SCIENCES. Society of Toxicology, 102(1):15-32, (2008).
2007
BARTON, H. A., W. CHIU, R. W. SETZER, M. E. ANDERSEN, A. J. BAILER, F. Y. BOIS, R. DEWOSKIN, S. HAYS, G. JOHANSON, N. JONES, G. LOIZOU, R. C. MACPHAIL, C. J. PORTIER, M. SPENDIFF, AND Y. TAN. CHARACTERIZING UNCERTAINTY AND VARIABILITY IN PBPK MODELS: STATE OF THE SCIENCE AND NEEDS FOR RESEARCH AND IMPLEMENTATION. doi:10.1093/toxsci Oxford University Press (ed.), TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 99(2)(May):395-402, (2007).
BARTON, H. A., W. CHIU, R. W. SETZER, M. E. Andersen, A. J. Bailer, F. Y. Bois, R. S. DeWoskin, S. Hays, G. Johanson, N. Jones, G. Loizou, C. Portier, M. Spendiff, AND Y. Tan. Characterizing Uncertainty and Variability in PBPK Models: State of the Science and Needs for Research and Implementation. TOXICOLOGICAL SCIENCES. Society of Toxicology, 99(2):395-402, (2007).


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