Records 1 to 25 of 79 for search term "ToxCast"
Yang, C., A. Tarkhov, J. Marusczyk1, B. Bienfait, J. Gasteiger, T. Kleinoeder, T. Magdziarz, O. Sacher, C. Schwab, J. Schwoebel, L. Terfloth, K. Arvidson, A. Richard, A. Worth, AND J. Rathman. A New Publicly Available Chemical Query Language, CSRML, to support Chemotype Representations for Application to Data-Mining and Modeling. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 55(3):510-528, (2015).
Trisciuzzi, D., D. Alberga, K. Mansouri, R. Judson, S. Cellamare, M. Catto, A. Carotti, E. Benfenati, E. Novellino, G. Mangiatordi, AND O. Nicolotti. Docking-based classification models for exploratory toxicology studies on high-quality estrogenic experimental data. Future Medicinal Chemistry. Future Science Group, London, Uk, 7(14):1921-1936, (2015).
Knudsen, T., D. Keller, M. Sander, E. Carney, N. Doerrer, D. Eaton, S. Fitzpatrick, K. Hastings, D. Mendric, R. Tice, P. Watkins, AND M. Whelan. FORUM - FutureTox II: In vitro Data and In Silico Models forPredictive Toxicology. TOXICOLOGICAL SCIENCES. Society of Toxicology, 143(2):256–267, (2015).
Wetmore, B., John F. Wambaugh, B. Allen, S. Ferguson, M. Sochaski, R. Woodrow Setzer, Keith A. Houck, C. Strope, K. Cantwell, Richard S. Judson, E. LeCluyse, H. Clewell III, Russell S. Thomas, AND M. Andersen. Incorporating High-Throughput Exposure Predictions with Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. TOXICOLOGICAL SCIENCES. Society of Toxicology, 1-57, (2015).
Judson, Richard S., F. Magpantay, V. Chickarmane, C. Haskell, N. Tania, J. Taylor, M. Xia, R. Huang, D. Rotroff, D. Filer, K. Houck, M. Martin, N. Sipes, A. Richard, K. Mansouri, W. Setzer, T. Knudsen, K. Crofton, AND R. Thomas. Integrated Model of Chemical Perturbations of a Biological PathwayUsing 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor. TOXICOLOGICAL SCIENCES. Society of Toxicology, :1-42, (2015).
Bal-Price, A., K. Crofton, M. Leist, S. Allen, M. Arand, T. Buetler, N. Delrue, R. FitzGerald, T. Hartung, T. Heinonen, H. Hogberg, S. Hougaard Bennekou, W. Lichtensteiger, D. Oggier, M. Paparella, M. Axelstad, A. Piersma, E. Rached, B. Schilter, G. Schmuck, L. Stoppini, E. Tongiorgi, M. Tiramani, F. Monnet-Tschudi, M. Wilks, T. Ylikomi, AND E. Fritsche. International STakeholder NETwork (ISTNET): Creating a Developmental Neurotoxicity Testing (DNT) Roadmap for Regulatory Purposes. Archives of Toxicology. Springer, New York, NY, 89(2):269-287, (2015).
Liu, J., K. Mansouri, Richard S. Judson, Matthew T. Martin, H. Hong, M. Chen, X. Xu, Russell S. Thomas, AND I. Shah. Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 28(4):738-751, (2015).
Attene-Ramos, M., R. Huang, S. Michael, K. Witt, A. Richard, R. Tice, A. Simeonov, C. Austin, AND M. Xia. Profiling of the Tox21 Chemical Collection for Mitochondrial Function: I. Compounds that Decrease Mitochondrial Membrane Potential. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 123(1):49-56, (2015).
Browne, P., R. Judson, W. Casey, N. Kleinstreuer, AND R. Thomas. SCREENING CHEMICALS FOR ESTROGEN RECEPTOR BIOACTIVITY USING A COMPUTATIONAL MODEL. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 49(14):8804-8814, (2015).
Leung, M., J. Phuong, N. Baker, N. Sipes, G. Klinefelter, M. Martin, K. McLaurin, W. Setzer, S. Darney, R. Judson, AND T. Knudsen. Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, , 1-47, (2015).
Wambaugh, J., B. Wetmore, R. Pearce, C. Strope, R. Goldsmith, J. Sluka, A. Sedykh, A. Tropsha, S. Bosgra, I. Shah, R. Judson, R. Thomas, AND W. Setzer. Toxicokinetic Triage for Environmental Chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, 147(1):55-67, (2015).
Shah, I., W. Setzer, J. Jack, K. Houck, R. Judson, T. Knudsen, J. Liu, M. Martin, D. Reif, Ann M. Richard, Russell S. Thomas, K. Crofton, David J. Dix, AND Robert J. Kavlock. Using ToxCast data to reconstruct dynamic cell state trajectories and estimate toxicological points of departure. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, , 1-33, (2015).
Tollefsena, K., S. Scholz, M. Cronin, S. Edwards, J. de Knecht, K. Crofton, N. Garcia-Reyero, T. Hartung, A. Worth, AND C. Patlewicz. Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA workshop report). REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 70(3):629-640, (2014).
Paul, K., J. Hedge, D. Rotroff, M. Hornung, K. Crofton, AND Steve Simmons. Development of a thyroperoxidase inhibition assay for high-throughput screening. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 27(3):387-99, (2014).
Judson, R., K. Houck, M. Martin, T. Knudsen, R. Thomas, N. Sipes, I. Shah, J. Wambaugh, AND K. Crofton. In Vitro and Modeling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Program. BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. Blackwell Publishing, Malden, MA, 115(1):69-76, (2014).
Wetmore, B., B. Allen, H. Clewell III, T. Parker, John F. Wambaugh, L. Almond, M. Sochaski, AND Russell S. Thomas. Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing. TOXICOLOGICAL SCIENCES. Society of Toxicology, 142(1):210-224, (2014).
Kleensang, A., A. Maertens, M. Rosenberg, S. Fitzpatrick, J. Lamb, S. Auerbach, R. Brennan, K. Crofton, B. Gordon, A. Fornance, K. Gaido, D. Gerhold, R. Haw, A. Henney, A. Ma’ayan, M. McBride, S. Monti, M. Ochs, A. Pandey, R. Sharan, R. Stierum, S. Tugendreich, C. Willett, C. Wittwehr, J. Xia, G. Patton, K. Arvidson, M. Bouhifd, H. Hogberg, T. Luechtefeld, L. Smirnova, L. Zhao, Y. Adeleye, M. Kanehisa, P. Carmichael, M. Andersen, AND T. Hartung. Pathways of Toxicity. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 31(1):53-61, (2014).
Kleinstreuer, N., J. Yang, E. Berg, T. Knudsen, A. Richard, M. Martin, D. Reif, R. Judson, M. Polokoff, D. Dix, R. Kavlock, AND K. Houck. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nature Biotechnology. Elsevier Science, New York, NY, 32(6):583-591, (2014).
Rotroff, D., M. Martin, D. Dix, D. Filer, K. Houck, T. Knudsen, N. Sipes, D. Reif, M. Xia, R. Huang, AND R. Judson. Predictive Endocrine Testing in the 21st Century Using In Vitro Assays of Estrogen Receptor Signaling Responses. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 48:8706-8716, (2014).
Filer, D., H. Patisaul, T. Schug, D. Reif, AND K. Thayer. Test driving ToxCast: endocrine profiling for1858 chemicals included in phase II. Current Opinion in Pharmacology. Elsevier B.V., Amsterdam, Netherlands, 19(12):145-152, (2014).
KLEINSTREUER, N., D. J. DIX, M. ROUNTREE, N. BAKER, N. SIPES, D. REIF, R. SPENCER, AND T. B. KNUDSEN. A Computational Model Predicting Disruption of Blood Vessel Development. Shayn M.Pierce (ed.), PLoS Computational Biology. Public Library of Science, San Francisco, CA, 9(4):1-20, (2013).
Nel, A., E. Nasser, H. Godwin, D. Avery, T. Bahadori, L. Bergeson, E. Beryt, J. Bonner, D. Boverhof, J. Carter, V. Castranova, J. DeShazo, S. Hussain, A. Kane, F. Klaessig, E. Kuempel, M. Lafranconi, R. Landsiede, T. Malloy, M. Miller, J. Morris, K. Moss, G. Oberdorster, K. Pinkerton, R. Pleus, J. Shatkin, R. Thomas, T. Tolaymat, A. Wang, AND J. Wong. A Multi-Stakeholder Perspective on the Use of Alternative Test Strategies for Nanomaterial Safety Assessment (workshop report). ACS Nano. American Chemical Society, Washington, DC, 7(8):6422–6433, (2013).
Zang, Q., D. Rotroff, AND R. Judson. Binary Classification of a Large Collection of Environmental Chemicals from Estrogen Receptor Assays by Quantitative Structure-Activity Relationship and Machine Learning Methods. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 53:3244−3261, (2013).
WAMBAUGH, J. F., W. SETZER, A. M. Pitruzzello, J. Liu, D. M. Reif, N. C. Kleinstreuer, N. Y. WANG, N. SIPES, M. T. MARTIN, K. DAS, J. C. DeWitt, M. STRYNAR, R. JUDSON, K. A. HOUCK, AND C. LAU. Dosimetric Anchoring of In Vivo and In Vitro Studies for Perfluorooctanoate and Perfluorooctanesulfonate. TOXICOLOGICAL SCIENCES. Society of Toxicology, 136(2):308-327, (2013).
WAMBAUGH, J. F., R. W. SETZER, D. REIF, S. GANGWAL, J. MITCHELLBLACKWOOD, J. A. ARNOT, O. JOLIET, A. FRAME, J. R. RABINOWITZ, T. B. KNUDSEN, R. S. JUDSON, P. P. EGEGHY, D. A. VALLERO, AND E. A. COHEN HUBAL. High-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project . Jerald Schnoor (ed.), ENVIRONMENTAL SCIENCE AND TECHNOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 47(15):8479-8488, (2013).