Records 1 to 25 of 183
Yang, C., A. Tarkhov, J. Marusczyk1, B. Bienfait, J. Gasteiger, T. Kleinoeder, T. Magdziarz, O. Sacher, C. Schwab, J. Schwoebel, L. Terfloth, K. Arvidson, A. Richard, A. Worth, AND J. Rathman. A New Publicly Available Chemical Query Language, CSRML, to support Chemotype Representations for Application to Data-Mining and Modeling. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 55(3):510-528, (2015).
Aoyama, H., N. Takahashi, Y. Shutoh, A. Motomura, AND K. Crofton. Developmental Neurotoxicology: History and Outline of Developmental Neurotoxicity Study Guidelines. Food Safety. Food Safety Commission, Cabinet Office, Government of Japan, TOKYO, Japan, 3(2):48-61, (2015).
Knudsen, T., D. Keller, M. Sander, E. Carney, N. Doerrer, D. Eaton, S. Fitzpatrick, K. Hastings, D. Mendric, R. Tice, P. Watkins, AND M. Whelan. FORUM - FutureTox II: In vitro Data and In Silico Models forPredictive Toxicology. TOXICOLOGICAL SCIENCES. Society of Toxicology, 143(2):256–267, (2015).
Garcia, R., J. Ibrahim, J. Wambaugh, E. Kenyon, AND W. Setzer. Identifiability of PBPK Models with Applications to Dimethylarsinic Acid Exposure. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. Springer, New York, NY, , 1-19, (2015).
Wetmore, B., John F. Wambaugh, B. Allen, S. Ferguson, M. Sochaski, R. Woodrow Setzer, Keith A. Houck, C. Strope, K. Cantwell, Richard S. Judson, E. LeCluyse, H. Clewell III, Russell S. Thomas, AND M. Andersen. Incorporating High-Throughput Exposure Predictions with Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. TOXICOLOGICAL SCIENCES. Society of Toxicology, 1-57, (2015).
Judson, Richard S., F. Magpantay, V. Chickarmane, C. Haskell, N. Tania, J. Taylor, M. Xia, R. Huang, D. Rotroff, D. Filer, K. Houck, M. Martin, N. Sipes, A. Richard, K. Mansouri, W. Setzer, T. Knudsen, K. Crofton, AND R. Thomas. Integrated Model of Chemical Perturbations of a Biological PathwayUsing 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor. TOXICOLOGICAL SCIENCES. Society of Toxicology, :1-42, (2015).
Bal-Price, A., K. Crofton, M. Leist, S. Allen, M. Arand, T. Buetler, N. Delrue, R. FitzGerald, T. Hartung, T. Heinonen, H. Hogberg, S. Hougaard Bennekou, W. Lichtensteiger, D. Oggier, M. Paparella, M. Axelstad, A. Piersma, E. Rached, B. Schilter, G. Schmuck, L. Stoppini, E. Tongiorgi, M. Tiramani, F. Monnet-Tschudi, M. Wilks, T. Ylikomi, AND E. Fritsche. International STakeholder NETwork (ISTNET): Creating a Developmental Neurotoxicity Testing (DNT) Roadmap for Regulatory Purposes. Archives of Toxicology. Springer, New York, NY, 89(2):269-287, (2015).
Liu, J., K. Mansouri, Richard S. Judson, Matthew T. Martin, H. Hong, M. Chen, X. Xu, Russell S. Thomas, AND I. Shah. Predicting hepatotoxicity using ToxCast in vitro bioactivity and chemical structure. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 28(4):738-751, (2015).
Attene-Ramos, M., R. Huang, S. Michael, K. Witt, A. Richard, R. Tice, A. Simeonov, C. Austin, AND M. Xia. Profiling of the Tox21 Chemical Collection for Mitochondrial Function: I. Compounds that Decrease Mitochondrial Membrane Potential. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 123(1):49-56, (2015).
Browne, P., R. Judson, W. Casey, N. Kleinstreuer, AND R. Thomas. SCREENING CHEMICALS FOR ESTROGEN RECEPTOR BIOACTIVITY USING A COMPUTATIONAL MODEL. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 49(14):8804-8814, (2015).
Daston, G., D. Knight, M. Schwarz, T. Gocht, R. Thomas, C. Mahony, AND M. Whelan. SEURAT: Safety Evaluation Ultimately Replacing Animal Testing – Recommendations for future research in the field of predictive toxicology. Archives of Toxicology. Springer, New York, NY, 89(1):15-23, (2015).
Bouhifd, M., M. Andersen, C. Baghdikian, K. Boekelheide, K. Crofton, A. Fornace Jr., A. Kleensang, H. Li, C. Livi, A. Maertens, P. McMullen, M. Rosenberg, R. Thomas, M. Vantangoli, J. Yager, L. Zhao, AND T. Hartung. The Human Toxome Project. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 32:112-124, (2015).
Gocht, T., E. Berggren, H. Ahr, I. Cotgreave, M. Cronin, G. Daston, B. Hardy, E. Heinzle, J. Hescheler, D. Knight, C. Mahony, M. Peschanski, M. Schwarz, R. Thomas, C. Verfaillie, A. White, AND M. Whelan. The SEURAT-1 Approach towards Animal Free Human Safety Assessment. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 32(1):9-24, (2015).
Wambaugh, J., B. Wetmore, R. Pearce, C. Strope, R. Goldsmith, J. Sluka, A. Sedykh, A. Tropsha, S. Bosgra, I. Shah, R. Judson, R. Thomas, AND W. Setzer. Toxicokinetic Triage for Environmental Chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, 147(1):55-67, (2015).
Tollefsena, K., S. Scholz, M. Cronin, S. Edwards, J. de Knecht, K. Crofton, N. Garcia-Reyero, T. Hartung, A. Worth, AND C. Patlewicz. Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA workshop report). REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 70(3):629-640, (2014).
Leist, M., N. Hasiwa, C. Rovida, M. Daneshian, D. Basketter, I. Kimber, H. Clewell, T. Gocht, A. Goldberg, F. Busquet, A. Rossi, M. Schwarz, M. Stephens, R. Taalman, T. Knudsen, J. McKim, G. Harris, D. Pamies, AND T. Hartung. Consensus report on the future of animal-free systemic toxicity testing. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 31(3):341-356, (2014).
Goldsmith, Rocky, C. Grulke, R. Brooks, T. Transue, C. Tan, A. Frame, P. Egeghy, R. Edwards, D. Chang, R. Tornero-Velez, K. Isaacs, A. Wang, J. Johnson, K. Holm, M. Reich, J. Mitchell, D. Vallero, L. Phillips, M. Phillips, J. Wambaugh, R. Judson, T. Buckley, AND C. Dary. Development of a Consumer Product Ingredient Database for Chemical ExposureScreening and Prioritization. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 65:269-279, (2014).
Paul, K., J. Hedge, D. Rotroff, M. Hornung, K. Crofton, AND Steve Simmons. Development of a thyroperoxidase inhibition assay for high-throughput screening. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 27(3):387-99, (2014).
Goldsmith, M., C. Grulke, D. Chang, T. Transue, S. Little, J. Rabinowitz, AND R. Tornero-Velez. DockScreen: A database of in silico biomolecular interactions to support computational toxicology. Dataset Papers in Science. Hindawi Publishing Corporation, New York, NY, 2014:1-5, (2014).
Wambaugh, J., A. Wang, A. Frame, K. Dionisio, P. Egeghy, R. Judson, AND W. Setzer. High Throughput Heuristics for Prioritizing Human Exposure to Environmental Chemicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 48:12760-12767, (2014).
Tal, T., C. McCollum, P. Harris, J. Olin, N. Kleinstreuer, C. Wood, C. Hans, S. Shah, F. Merchant, M. Bondesson, T. Knudsen, S. Padilla, AND M. Hemmer. Immediate and long-term consequences of vascular toxicity during zebrafish development. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 48:51-61, (2014).
Judson, R., K. Houck, M. Martin, T. Knudsen, R. Thomas, N. Sipes, I. Shah, J. Wambaugh, AND K. Crofton. In Vitro and Modeling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Program. BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. Blackwell Publishing, Malden, MA, 115(1):69-76, (2014).
Wetmore, B., B. Allen, H. Clewell III, T. Parker, John F. Wambaugh, L. Almond, M. Sochaski, AND Russell S. Thomas. Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing. TOXICOLOGICAL SCIENCES. Society of Toxicology, 142(1):210-224, (2014).
Kleensang, A., A. Maertens, M. Rosenberg, S. Fitzpatrick, J. Lamb, S. Auerbach, R. Brennan, K. Crofton, B. Gordon, A. Fornance, K. Gaido, D. Gerhold, R. Haw, A. Henney, A. Ma’ayan, M. McBride, S. Monti, M. Ochs, A. Pandey, R. Sharan, R. Stierum, S. Tugendreich, C. Willett, C. Wittwehr, J. Xia, G. Patton, K. Arvidson, M. Bouhifd, H. Hogberg, T. Luechtefeld, L. Smirnova, L. Zhao, Y. Adeleye, M. Kanehisa, P. Carmichael, M. Andersen, AND T. Hartung. Pathways of Toxicity. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 31(1):53-61, (2014).
Kleinstreuer, N., J. Yang, E. Berg, T. Knudsen, A. Richard, M. Martin, D. Reif, R. Judson, M. Polokoff, D. Dix, R. Kavlock, AND K. Houck. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nature Biotechnology. Elsevier Science, New York, NY, 32(6):583-591, (2014).