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Records 1 to 25 of 174
COTE, I. L., P. T. ANASTAS, L. S. BIRNBAUM, B. A. CLARK, D. J. DIX, S. W. EDWARDS, AND P. W. PREUSS. Advancing the Next Generation of Health Risk Assessment. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 120(11):1499-1502, (2013).
Yang, C., A. Tarkhov, J. Marusczyk1, B. Bienfait, J. Gasteiger, T. Kleinoeder, T. Magdziarz, O. Sacher, C. Schwab, J. Schwoebel, L. Terfloth, K. Arvidson, A. Richard, A. Worth, AND J. Rathman. A New Publicly Available Chemical Query Language, CSRML, to support Chemotype Representations for Application to Data-Mining and Modeling. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 55(3):510-528, (2015).
Attene-Ramos, M., R. Huang, S. Michael, K. Witt, A. Richard, R. Tice, A. Simeonov, C. Austin, AND M. Xia. Profiling of the Tox21 Chemical Collection for Mitochondrial Function: I. Compounds that Decrease Mitochondrial Membrane Potential. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 123(1):49-56, (2015).
Daston, G., D. Knight, M. Schwarz, T. Gocht, R. Thomas, C. Mahony, AND M. Whelan. SEURAT: Safety Evaluation Ultimately Replacing Animal Testing – Recommendations for future research in the field of predictive toxicology. Archives of Toxicology. Springer, New York, NY, 89(1):15-23, (2015).
Gocht, T., E. Berggren, H. Ahr, I. Cotgreave, M. Cronin, G. Daston, B. Hardy, E. Heinzle, J. Hescheler, D. Knight, C. Mahony, M. Peschanski, M. Schwarz, R. Thomas, C. Verfaillie, A. White, AND M. Whelan. The SEURAT-1 Approach towards Animal Free Human Safety Assessment. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 32(1):9-24, (2015).
Filer, D., H. Patisaul, T. Schug, D. Reif, AND K. Thayer. An Expanded Model for Endocrine Profiling Using ToxCast Screening Data for 1858 Chemicals. Current Opinion in Pharmacology. Elsevier B.V., Amsterdam, Netherlands, 19(12):145-152, (2014).
Tollefsena, K., S. Scholz, M. Cronin, S. Edwards, J. de Knecht, K. Crofton, N. Garcia-Reyero, T. Hartung, A. Worth, AND C. Patlewicz. Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA workshop report). REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 70(3):629-640, (2014).
Leist, M., N. Hasiwa, C. Rovida, M. Daneshian, D. Basketter, I. Kimber, H. Clewell, T. Gocht, A. Goldberg, F. Busquet, A. Rossi, M. Schwarz, M. Stephens, R. Taalman, T. Knudsen, J. McKim, G. Harris, D. Pamies, AND T. Hartung. Consensus report on the future of animal-free systemic toxicity testing. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 31(3):341-356, (2014).
Goldsmith, Rocky, C. Grulke, R. Brooks, T. Transue, C. Tan, A. Frame, P. Egeghy, R. Edwards, D. Chang, R. Tornero-Velez, K. Isaacs, A. Wang, J. Johnson, K. Holm, M. Reich, J. Mitchell, D. Vallero, L. Phillips, M. Phillips, J. Wambaugh, R. Judson, T. Buckley, AND C. Dary. Development of a Consumer Product Ingredient Database for Chemical ExposureScreening and Prioritization. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 65:269-279, (2014).
Paul, K., J. Hedge, D. Rotroff, M. Hornung, K. Crofton, AND Steve Simmons. Development of a thyroperoxidase inhibition assay for high-throughput screening. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 27(3):387-99, (2014).
Goldsmith, M., C. Grulke, D. Chang, T. Transue, S. Little, J. Rabinowitz, AND R. Tornero-Velez. DockScreen: A database of in silico biomolecular interactions to support computational toxicology. Dataset Papers in Science. Hindawi Publishing Corporation, New York, NY, 2014:1-5, (2014).
Wambaugh, J., A. Wang, A. Frame, K. Dionisio, P. Egeghy, R. Judson, AND W. Setzer. High Throughput Heuristics for Prioritizing Human Exposure to Environmental Chemicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 48:12760-12767, (2014).
Tal, T., C. McCollum, P. Harris, J. Olin, N. Kleinstreuer, C. Wood, C. Hans, S. Shah, F. Merchant, M. Bondesson, T. Knudsen, S. Padilla, AND M. Hemmer. Immediate and long-term consequences of vascular toxicity during zebrafish development. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 48:51-61, (2014).
Judson, R., K. Houck, M. Martin, T. Knudsen, R. Thomas, N. Sipes, I. Shah, J. Wambaugh, AND K. Crofton. In Vitro and Modeling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Program. BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. Blackwell Publishing, Malden, MA, 115(1):69-76, (2014).
Wetmore, B., B. Allen, H. Clewell III, T. Parker, John F. Wambaugh, L. Almond, M. Sochaski, AND Russell S. Thomas. Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing. TOXICOLOGICAL SCIENCES. Society of Toxicology, 142(1):210-224, (2014).
Kleensang, A., A. Maertens, M. Rosenberg, S. Fitzpatrick, J. Lamb, S. Auerbach, R. Brennan, K. Crofton, B. Gordon, A. Fornance, K. Gaido, D. Gerhold, R. Haw, A. Henney, A. Ma’ayan, M. McBride, S. Monti, M. Ochs, A. Pandey, R. Sharan, R. Stierum, S. Tugendreich, C. Willett, C. Wittwehr, J. Xia, G. Patton, K. Arvidson, M. Bouhifd, H. Hogberg, T. Luechtefeld, L. Smirnova, L. Zhao, Y. Adeleye, M. Kanehisa, P. Carmichael, M. Andersen, AND T. Hartung. Pathways of Toxicity. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 31(1):53-61, (2014).
Kleinstreuer, N., J. Yang, E. Berg, T. Knudsen, A. Richard, M. Martin, D. Reif, R. Judson, M. Polokoff, D. Dix, R. Kavlock, AND K. Houck. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nature Biotechnology. Elsevier Science, New York, NY, 32(6):583-591, (2014).
Rotroff, D., M. Martin, D. Dix, D. Filer, K. Houck, T. Knudsen, N. Sipes, D. Reif, M. Xia, R. Huang, AND R. Judson. Predictive Endocrine Testing in the 21st Century Using In Vitro Assays of Estrogen Receptor Signaling Responses. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 48:8706-8716, (2014).
Slob, W. AND W. Setzer. Shape and Steepness of Toxicological Dose-Response Relationships of Continuous Endpoints. CRITICAL REVIEWS IN TOXICOLOGY. CRC Press LLC, Boca Raton, FL, 44(3):270-297, (2014).
KLEINSTREUER, N., D. J. DIX, M. ROUNTREE, N. BAKER, N. SIPES, D. REIF, R. SPENCER, AND T. B. KNUDSEN. A Computational Model Predicting Disruption of Blood Vessel Development. Shayn M.Pierce (ed.), PLoS Computational Biology. Public Library of Science, San Francisco, CA, 9(4):1-20, (2013).
Nel, A., E. Nasser, H. Godwin, D. Avery, T. Bahadori, L. Bergeson, E. Beryt, J. Bonner, D. Boverhof, J. Carter, V. Castranova, J. DeShazo, S. Hussain, A. Kane, F. Klaessig, E. Kuempel, M. Lafranconi, R. Landsiede, T. Malloy, M. Miller, J. Morris, K. Moss, G. Oberdorster, K. Pinkerton, R. Pleus, J. Shatkin, R. Thomas, T. Tolaymat, A. Wang, AND J. Wong. A Multi-Stakeholder Perspective on the Use of Alternative Test Strategies for Nanomaterial Safety Assessment (workshop report). ACS Nano. American Chemical Society, Washington, DC, 7(8):6422–6433, (2013).
Zang, Q., D. Rotroff, AND R. Judson. Binary Classification of a Large Collection of Environmental Chemicals from Estrogen Receptor Assays by Quantitative Structure-Activity Relationship and Machine Learning Methods. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 53:3244−3261, (2013).
WAMBAUGH, J. F., W. SETZER, A. M. Pitruzzello, J. Liu, D. M. Reif, N. C. Kleinstreuer, N. Y. WANG, N. SIPES, M. T. MARTIN, K. DAS, J. C. DeWitt, M. STRYNAR, R. JUDSON, K. A. HOUCK, AND C. LAU. Dosimetric Anchoring of In Vivo and In Vitro Studies for Perfluorooctanoate and Perfluorooctanesulfonate. TOXICOLOGICAL SCIENCES. Society of Toxicology, 136(2):308-327, (2013).
Shen, J., L. Xu, H. Fang, A. M. RICHARD, J. D. Bray, R. JUDSON, G. Zhou, T. J. Colatsky, J. L. Aungst, C. Teng, S. C. Harris, W. Ge, AND S. Y. Dai. EADB: An Estrogenic Activity Database for Assessing Potential Endocrine Activity. TOXICOLOGICAL SCIENCES. Society of Toxicology, 135(2):277-291, (2013).
Paul, K., J. Thompson, Steve Simmons, J. Vanden Heuvel, AND K. Crofton. Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, 27(7):2049-2060, (2013).

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