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Records 1 to 25 of 53
KLEINSTREUER, N., D. J. DIX, M. ROUNTREE, N. BAKER, N. SIPES, D. REIF, R. SPENCER, AND T. B. KNUDSEN. A Computational Model Predicting Disruption of Blood Vessel Development. Shayn M.Pierce (ed.), PLoS Computational Biology. Public Library of Science, San Francisco, CA, 9(4):1-20, (2013).
JUDSON, R., A. M. RICHARD, D. J. DIX, K. A. HOUCK, F. Elloumi, M. T. MARTIN, T. Cathey, T. R. Transue, R. SPENCER, AND M. WOLF. ACToR-Aggregated Computational Resource. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 233(1):7-13, (2008).
KNUDSEN, T. B., K. A. HOUCK, N. SIPES, A. V. SINGH, R. JUDSON, M. T. MARTIN, A. WEISSMAN, N. KLEINSTREUER, H. M. MORTENSEN, D. REIF, J. R. RABINOWITZ, R. W. SETZER, A. M. RICHARD, D. J. DIX, AND R. J. KAVLOCK. Activity profiles of 309 ToxCastâ„¢ chemicals evaluated across 292 biochemical targets. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 282(1-2):1-15, (2011).
JUDSON, R., M. T. MARTIN, D. REIF, K. A. HOUCK, T. B. KNUDSEN, D. ROTROFF, M. XIA, S. SAKAMURU, R. HUANG, P. SHINN, C. P. AUSTIN, R. J. KAVLOCK, AND D. J. DIX. Analysis of Eight Oil Spill Dispersants Using Rapid, In Vitro Tests for Endocrine and Other Biological Activity. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 44(15):5979-5985, (2010).
HUANG, R., M. XIA, M. CHO, S. SAKAMURU, P. SHINN, K. A. HOUCK, D. J. DIX, R. JUDSON, K. L. WITT, R. J. KAVLOCK, R. R. TICE, AND C. P. AUSTIN. Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(8):1142-1148, (2011).
PIERSMA, A. H., E. RORIJE, M. E. BEEKHUIJZEN, R. L. COOPER, D. J. DIX, B. HEINRICH-HIRSCH, M. T. MARTIN, E. MENDEZ, A. MULLER, M. PAPARELLA, D. RAMSINGH, E. REAVES, P. RIDGWAY, E. SCHENK, L. STACHIW, B. ULBRICH, AND B. C. HAKKERT. Combined retrospective analysis of 498 rat multi-generation reproductive toxicity studies: on the impact of parameters related to F1 mating and F2 offspring. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 31(4):392-401, (2011).
KAVLOCK, R. J., G. T. ANKLEY, J. N. BLANCATO, M. BREEN, R. CONOLLY, D. J. DIX, K. A. HOUCK, E. A. COHEN-HUBAL, R. JUDSON, J. R. RABINOWITZ, A. M. RICHARD, R. W. SETZER, I. A. SHAH, D. L. VILLENEUVE, AND E. J. WEBER. Computational Toxicology - A State of the Science Mini Review. TOXICOLOGICAL SCIENCES. Society of Toxicology, 103(1):14-27, (2008).
KAVLOCK, R. J. AND D. J. DIX. Computational Toxicology as Implemented by the U.S. EPA: Providing High Throughput Decision Support Tools for Screening and Assessing Chemical Exposure, Hazard and Risk. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 1(2-4):197-217, (2010).
GOETZ, A., H. REN, J. E. SCHMID, C. R. BLYSTONE, I. THILLAINADARAJAH, D. S. BEST, H. P. NICHOLS, L. STRADER, D. C. WOLF, M. G. NAROTSKY, J. C. ROCKETT, AND D. J. DIX. DISRUPTION OF TESTOSTERONE HOMEOSTASIS AS A MODE OF ACTION FOR THE REPRODUCTIVE TOXICITY OF TRIAZOLE FUNGICIDES IN THE MALE RAT. Amber K. Goetz; David Dix (ed.), TOXICOLOGY SCIENCE. Oxford University Press, Cary, NC, 95(October):227-239, (2007).
MARTIN, M. T., T. B. KNUDSEN, R. JUDSON, R. J. KAVLOCK, AND D. J. DIX. Economic benefits of using adaptive predictive models of reproductive toxicity in the context of a tiered testing program . Stephen A. Krawetz (Editor-in-Chief) (ed.), Systems Biology in Reproductive Medicine. Informa Healthcare USA, New York, NY, 58(1):3-9, (2012).
Wrench, N., C. R. Pinto, G. R. KLINEFELTER, D. J. DIX, W. L. Flowers, AND C. E. Farin. Effect of season on fresh and cryopreserved stallion semen. Animal Reproduction Science. Elsevier BV, AMSTERDAM, Netherlands, 119(3-4):219-227, (2010).
REIF, D., M. T. MARTIN, S. TAN, K. A. HOUCK, R. JUDSON, A. M. RICHARD, T. B. KNUDSEN, D. J. DIX, AND R. J. KAVLOCK. Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(12):2-8, (2010).
KLEINSTREUER, N. C., R. S. JUDSON, D. M. REIF, N. S. SIPES, A. V. SINGH, K. J. CHANDLER, R. DEWOSKIN, D. J. DIX, R. J. KAVLOCK, AND T. B. KNUDSEN. Environmental Impact on Vascular Development Predicted by High Throughput Screening. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(11):1596-1603, (2011).
JUDSON, R., R. J. KAVLOCK, R. W. SETZER, E. A. COHEN-HUBAL, M. T. MARTIN, T. B. KNUDSEN, K. A. HOUCK, R. S. THOMAS, B. A. WETMORE, AND D. J. DIX. Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 24(4):451-462, (2011).
CHANDLER, K. J., M. BARRIER, S. C. JEFFAY, H. P. NICHOLS, N. KLEINSTREUER, A. Singh, D. REIF, N. SIPES, R. JUDSON, D. J. DIX, R. J. KAVLOCK, E. S. HUNTER, AND T. Knudsen. Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay. PLoS ONE . Public Library of Science, San Francisco, CA, 6(6):e1840, (2011).
KNIGHT, A. W., S. LITTLE, K. A. HOUCK, D. J. DIX, R. JUDSON, A. M. RICHARD, N. MCCARROLL, G. AKERMAN, C. YANG, L. BIRRELL, AND R. M. WALMSLEY. Evaluation of High-throughput Genotoxicity Assays Used in Profiling the US EPA ToxCast Chemicals. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 55(2):188-99, (2009).
GOETZ, A., W. BAO, H. REN, J. E. SCHMID, D. B. TULLY, C. R. WOOD, J. C. ROCKETT, M. G. NAROTSKY, G. SUN, G. LAMBERT, S. THAI, D. C. WOLF, S. NESNOW, AND D. J. DIX. GENE EXPRESSION PROFILING IN THE LIVER OF CD-1 MICE TO CHARACTERIZE THE HEPATOTOXICITY OF TRIAZOLE FUNGICIDES. ScienceDirect Elsevier (ed.), TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 215(3):274-284, (2006).
WELCH, K. D., T. P. REILLY, M. BOURDI, T. HAYS, C. A. PISE-MASISON, M. R. RADONOVICH, J. N. BRADY, D. J. DIX, AND L. POHL. GENOMIC IDENTIFICATION OF POTENTIAL RISK FACTORS DURING ACETAMINOPHEN-INDUCED LIVER DISEASE IN SUSCEPTIBLE AND RESISTANT STRAINS OF MICE. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 19(July ):223-233, (2006).
TULLY, D. B., W. BAO, A. GOETZ, H. REN, J. E. SCHMID, C. R. BLYSTONE, L. F. STRADER, C. R. WOOD, D. S. BEST, M. G. NAROTSKY, S. BARONE, D. C. WOLF, J. C. ROCKETT, AND D. J. DIX. Gene Expression Profiling in Liver and Testis of Rats to Characterize the Toxicity of Triazole Fungicides. ScienceDirect Elsevier (ed.), TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 215(3):260-273, (2006).
KLEINSTREUER, N. C., A. M. SMITH, P. R. WEST, K. CONARD, B. FONTAINE, A. M. WEIR-HAUPTMAN, J. PALMER, T. B. KNUDSEN, D. J. DIX, E. L. DONLEY, AND G. G. CEZAR. Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics . TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier Science Inc., Burlington, MA, Online:1-10, (2011).
MARTIN, M. T., D. J. DIX, R. JUDSON, R. J. KAVLOCK, D. REIF, A. M. RICHARD, D. ROTROFF, S. ROMANOV, A. MEDVEDEV, N. POLTORATSKAYA, M. GAMBARIAN, M. MOESER, S. S. MAKAROV, AND K. A. HOUCK. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 23(3):578-90, (2010).
JUDSON, R., K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, H. M. MORTENSEN, D. REIF, D. ROTROFF, I. A. SHAH, A. M. RICHARD, AND D. J. DIX. In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(4):485-92, (2010).
KLEINSTREUER, N., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, K. B. PAUL, D. REIF, K. M. CROFTON, K. HAMILTON, R. HUNTER, I. A. SHAH, AND R. JUDSON. In vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, Epub(Advance Access):1-44, (2012).
DIX, D. J., K. A. HOUCK, R. JUDSON, N. KLEINSTREUER, T. B. KNUDSEN, M. T. MARTIN, D. REIF, A. M. RICHARD, I. A. SHAH, N. SIPES, AND R. J. KAVLOCK. Incorporating Biological, Chemical and Toxicological Knowledge into Predictive Models of Toxicity: Letter to the Editor. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 130(2):440-441, (2012).
ROTROFF, D. M., B. A. WETMORE, D. J. DIX, S. S. FERGUSON, H. J. CLEWELL, K. A. HOUCK, E. L. LECLUYSE, M. E. ANDERSEN, R. JUDSON, C. M. SMITH, M. A. SOCHASKI, R. J. KAVLOCK, F. BOELLMANN, M. T. MARTIN, D. REIF, J. F. WAMBAUGH, AND R. S. THOMAS. Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening . TOXICOLOGICAL SCIENCES. Society of Toxicology, 117(2):348-58, (2010).


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