Jump to main content or area navigation.

Contact Us

Computational Toxicology Research

Key Links
CompTox Home Basic Information Organization EPA Exposure Research Research Projects Chemical Databases ToxCast Stakeholder Events EPA Chemical Safety Research Research Publications Scientific Reviews Communities of Practice ToxCast Data Challenges Staff Profiles CompTox Partners Jobs and Opportunities
Records 1 to 25 of 51
JUDSON, R., F. Elloumi, R. W. SETZER, Z. Li, AND I. A. SHAH. A Comparison of Machine Learning Algorithms for Chemical Toxicity Classification Using a Simulated Multi-Scale Data Model. BMC Bioinformatics. BioMed Central Ltd, London, Uk, (9):241, (2008).
JUDSON, R., A. M. RICHARD, D. J. DIX, K. A. HOUCK, F. Elloumi, M. T. MARTIN, T. Cathey, T. R. Transue, R. SPENCER, AND M. WOLF. ACToR-Aggregated Computational Resource. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 233(1):7-13, (2008).
KNUDSEN, T. B., K. A. HOUCK, N. SIPES, A. V. SINGH, R. JUDSON, M. T. MARTIN, A. WEISSMAN, N. KLEINSTREUER, H. M. MORTENSEN, D. REIF, J. R. RABINOWITZ, R. W. SETZER, A. M. RICHARD, D. J. DIX, AND R. J. KAVLOCK. Activity profiles of 309 ToxCastâ„¢ chemicals evaluated across 292 biochemical targets. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 282(1-2):1-15, (2011).
JUDSON, R. S., M. T. MARTIN, P. P. EGEGHY, S. GANGWAL, D. M. REIF, P. KOTHIYA, M. A. WOLF, T. CATHEY, T. R. TRANSUE, D. SMITH, J. VAIL, A. FRAME, S. MOSHER, E. A. COHEN-HUBAL, AND A. M. RICHARD. Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System. International Journal of Molecular Sciences. MDPI AG, Basel, Switzerland, 13(2):1805-1831, (2012).
JUDSON, R., M. T. MARTIN, D. REIF, K. A. HOUCK, T. B. KNUDSEN, D. ROTROFF, M. XIA, S. SAKAMURU, R. HUANG, P. SHINN, C. P. AUSTIN, R. J. KAVLOCK, AND D. J. DIX. Analysis of Eight Oil Spill Dispersants Using Rapid, In Vitro Tests for Endocrine and Other Biological Activity. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 44(15):5979-5985, (2010).
Zang, Q., D. Rotroff, AND R. Judson. Binary Classification of a Large Collection of Environmental Chemicals from Estrogen Receptor Assays by Quantitative Structure-Activity Relationship and Machine Learning Methods. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 53:3244−3261, (2013).
HUANG, R., M. XIA, M. CHO, S. SAKAMURU, P. SHINN, K. A. HOUCK, D. J. DIX, R. JUDSON, K. L. WITT, R. J. KAVLOCK, R. R. TICE, AND C. P. AUSTIN. Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(8):1142-1148, (2011).
KAVLOCK, R. J., G. T. ANKLEY, J. N. BLANCATO, M. BREEN, R. CONOLLY, D. J. DIX, K. A. HOUCK, E. A. COHEN-HUBAL, R. JUDSON, J. R. RABINOWITZ, A. M. RICHARD, R. W. SETZER, I. A. SHAH, D. L. VILLENEUVE, AND E. J. WEBER. Computational Toxicology - A State of the Science Mini Review. TOXICOLOGICAL SCIENCES. Society of Toxicology, 103(1):14-27, (2008).
Goldsmith, Rocky, C. Grulke, R. Brooks, T. Transue, C. Tan, A. Frame, P. Egeghy, R. Edwards, D. Chang, R. Tornero-Velez, K. Isaacs, A. Wang, J. Johnson, K. Holm, M. Reich, J. Mitchell, D. Vallero, L. Phillips, M. Phillips, J. Wambaugh, R. Judson, T. Buckley, AND C. Dary. Development of a Consumer Product Ingredient Database for Chemical ExposureScreening and Prioritization. FOOD AND CHEMICAL TOXICOLOGY. Elsevier Science Ltd, New York, NY, 65:269-279, (2014).
WAMBAUGH, J. F., W. SETZER, A. M. Pitruzzello, J. Liu, D. M. Reif, N. C. Kleinstreuer, N. Y. WANG, N. SIPES, M. T. MARTIN, K. DAS, J. C. DeWitt, M. STRYNAR, R. JUDSON, K. A. HOUCK, AND C. LAU. Dosimetric Anchoring of In Vivo and In Vitro Studies for Perfluorooctanoate and Perfluorooctanesulfonate. TOXICOLOGICAL SCIENCES. Society of Toxicology, 136(2):308-327, (2013).
Shen, J., L. Xu, H. Fang, A. M. RICHARD, J. D. Bray, R. JUDSON, G. Zhou, T. J. Colatsky, J. L. Aungst, C. Teng, S. C. Harris, W. Ge, AND S. Y. Dai. EADB: An Estrogenic Activity Database for Assessing Potential Endocrine Activity. TOXICOLOGICAL SCIENCES. Society of Toxicology, 135(2):277-291, (2013).
MARTIN, M. T., T. B. KNUDSEN, R. JUDSON, R. J. KAVLOCK, AND D. J. DIX. Economic benefits of using adaptive predictive models of reproductive toxicity in the context of a tiered testing program . Stephen A. Krawetz (Editor-in-Chief) (ed.), Systems Biology in Reproductive Medicine. Informa Healthcare USA, New York, NY, 58(1):3-9, (2012).
REIF, D., M. T. MARTIN, S. TAN, K. A. HOUCK, R. JUDSON, A. M. RICHARD, T. B. KNUDSEN, D. J. DIX, AND R. J. KAVLOCK. Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(12):2-8, (2010).
KLEINSTREUER, N. C., R. S. JUDSON, D. M. REIF, N. S. SIPES, A. V. SINGH, K. J. CHANDLER, R. DEWOSKIN, D. J. DIX, R. J. KAVLOCK, AND T. B. KNUDSEN. Environmental Impact on Vascular Development Predicted by High Throughput Screening. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(11):1596-1603, (2011).
JUDSON, R., R. J. KAVLOCK, R. W. SETZER, E. A. COHEN-HUBAL, M. T. MARTIN, T. B. KNUDSEN, K. A. HOUCK, R. S. THOMAS, B. A. WETMORE, AND D. J. DIX. Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 24(4):451-462, (2011).
CHANDLER, K. J., M. BARRIER, S. C. JEFFAY, H. P. NICHOLS, N. KLEINSTREUER, A. Singh, D. REIF, N. SIPES, R. JUDSON, D. J. DIX, R. J. KAVLOCK, E. S. HUNTER, AND T. Knudsen. Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay. PLoS ONE . Public Library of Science, San Francisco, CA, 6(6):e1840, (2011).
KNIGHT, A. W., S. LITTLE, K. A. HOUCK, D. J. DIX, R. JUDSON, A. M. RICHARD, N. MCCARROLL, G. AKERMAN, C. YANG, L. BIRRELL, AND R. M. WALMSLEY. Evaluation of High-throughput Genotoxicity Assays Used in Profiling the US EPA ToxCast Chemicals. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 55(2):188-99, (2009).
Wambaugh, J., A. Wang, A. Frame, K. Dionisio, P. Egeghy, R. Judson, AND W. Setzer. High Throughput Heuristics for Prioritizing Human Exposure to Environmental Chemicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 48:12760-12767, (2014).
WAMBAUGH, J. F., R. W. SETZER, D. REIF, S. GANGWAL, J. MITCHELLBLACKWOOD, J. A. ARNOT, O. JOLIET, A. FRAME, J. R. RABINOWITZ, T. B. KNUDSEN, R. S. JUDSON, P. P. EGEGHY, D. A. VALLERO, AND E. A. COHEN HUBAL. High-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project . Jerald Schnoor (ed.), ENVIRONMENTAL SCIENCE AND TECHNOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 47(15):8479-8488, (2013).
MARTIN, M. T., D. J. DIX, R. JUDSON, R. J. KAVLOCK, D. REIF, A. M. RICHARD, D. ROTROFF, S. ROMANOV, A. MEDVEDEV, N. POLTORATSKAYA, M. GAMBARIAN, M. MOESER, S. S. MAKAROV, AND K. A. HOUCK. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 23(3):578-90, (2010).
JUDSON, R., K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, H. M. MORTENSEN, D. REIF, D. ROTROFF, I. A. SHAH, A. M. RICHARD, AND D. J. DIX. In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(4):485-92, (2010).
Judson, R., K. Houck, M. Martin, T. Knudsen, R. Thomas, N. Sipes, I. Shah, J. Wambaugh, AND K. Crofton. In Vitro and Modeling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Program. BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. Blackwell Publishing, Malden, MA, 115(1):69-76, (2014).
KLEINSTREUER, N., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, K. B. PAUL, D. REIF, K. M. CROFTON, K. HAMILTON, R. HUNTER, I. A. SHAH, AND R. JUDSON. In vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, Epub(Advance Access):1-44, (2012).
DIX, D. J., K. A. HOUCK, R. JUDSON, N. KLEINSTREUER, T. B. KNUDSEN, M. T. MARTIN, D. REIF, A. M. RICHARD, I. A. SHAH, N. SIPES, AND R. J. KAVLOCK. Incorporating Biological, Chemical and Toxicological Knowledge into Predictive Models of Toxicity: Letter to the Editor. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 130(2):440-441, (2012).
ROTROFF, D. M., B. A. WETMORE, D. J. DIX, S. S. FERGUSON, H. J. CLEWELL, K. A. HOUCK, E. L. LECLUYSE, M. E. ANDERSEN, R. JUDSON, C. M. SMITH, M. A. SOCHASKI, R. J. KAVLOCK, F. BOELLMANN, M. T. MARTIN, D. REIF, J. F. WAMBAUGH, AND R. S. THOMAS. Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening . TOXICOLOGICAL SCIENCES. Society of Toxicology, 117(2):348-58, (2010).


Jump to main content.