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Records 1 to 25 of 38
Yang, C., A. Tarkhov, J. Marusczyk1, B. Bienfait, J. Gasteiger, T. Kleinoeder, T. Magdziarz, O. Sacher, C. Schwab, J. Schwoebel, L. Terfloth, K. Arvidson, A. Richard, A. Worth, AND J. Rathman. A New Publicly Available Chemical Query Language, CSRML, to support Chemotype Representations for Application to Data-Mining and Modeling. Journal of Chemical Information and Modeling. American Chemical Society, Washington, DC, 55(3):510-528, (2015).
Benigni, R., C. Bossa, A. M. RICHARD, AND C. Yang. A Novel Approach: Chemical Relational Databases, and the Role of the ISSCAN Database on Assessing Chemical Carcinogenity. Annals of the Institute of Superiore Sanita 44(1):48-56, (2008).
Zhu, H., L. Ye, A. M. RICHARD, A. Golbraikh, F. A. Wright, I. Rusyn, AND A. Tropsha. A Novel Two-Step Hierarchial Quantitative Structure-Activity Relationship Modeling Workflow for Predicting Acute Toxicity of Chemicals in Rodents. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 117:1257-1264, (2009).
JUDSON, R., A. M. RICHARD, D. J. DIX, K. A. HOUCK, F. Elloumi, M. T. MARTIN, T. Cathey, T. R. Transue, R. SPENCER, AND M. WOLF. ACToR-Aggregated Computational Resource. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, 233(1):7-13, (2008).
KNUDSEN, T. B., K. A. HOUCK, N. SIPES, A. V. SINGH, R. JUDSON, M. T. MARTIN, A. WEISSMAN, N. KLEINSTREUER, H. M. MORTENSEN, D. REIF, J. R. RABINOWITZ, R. W. SETZER, A. M. RICHARD, D. J. DIX, AND R. J. KAVLOCK. Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 282(1-2):1-15, (2011).
COHEN-HUBAL, E. A., A. M. RICHARD, L. AYLWARD, S. W. EDWARDS, J. GALLAGHER, M. GOLDSMITH, S. ISUKAPALLI, R. TORNERO-VELEZ, E. J. WEBER, AND R. J. KAVLOCK. Advancing Exposure Characterization for Chemical Evaluation and Risk Assessment. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH - PART B: CRITICAL REVIEWS. Taylor & Francis, Inc., Philadelphia, PA, 13(2):299-313, (2010).
JUDSON, R. S., M. T. MARTIN, P. P. EGEGHY, S. GANGWAL, D. M. REIF, P. KOTHIYA, M. A. WOLF, T. CATHEY, T. R. TRANSUE, D. SMITH, J. VAIL, A. FRAME, S. MOSHER, E. A. COHEN-HUBAL, AND A. M. RICHARD. Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System. International Journal of Molecular Sciences. MDPI AG, Basel, Switzerland, 13(2):1805-1831, (2012).
RICHARD, A. M., L. SWIRSKY GOLD, AND M. C. NICKLAUS. CHEMICAL STRUCTURE INDEXING OF TOXICITY DATA ON THE INTERNET: MOVING TOWARDS A FLAT WORLD. CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT. BioMed Central Ltd, London, Uk, 9(3):314-325, (2006).
KAVLOCK, R. J., G. T. ANKLEY, J. N. BLANCATO, M. BREEN, R. CONOLLY, D. J. DIX, K. A. HOUCK, E. A. COHEN-HUBAL, R. JUDSON, J. R. RABINOWITZ, A. M. RICHARD, R. W. SETZER, I. A. SHAH, D. L. VILLENEUVE, AND E. J. WEBER. Computational Toxicology - A State of the Science Mini Review. TOXICOLOGICAL SCIENCES. Society of Toxicology, 103(1):14-27, (2008).
WILLIAMS, C., M. WOLF, AND A. M. RICHARD. DSSTox chemical-index files for exposure-related experiments in ArrayExpress and Gene Expression Omnibus: enabling toxico-chemogenomics data linkages. BIOINFORMATICS. Oxford University Press, Cary, NC, 25(5):692-694, (2009).
Shen, J., L. Xu, H. Fang, A. M. RICHARD, J. D. Bray, R. JUDSON, G. Zhou, T. J. Colatsky, J. L. Aungst, C. Teng, S. C. Harris, W. Ge, AND S. Y. Dai. EADB: An Estrogenic Activity Database for Assessing Potential Endocrine Activity. TOXICOLOGICAL SCIENCES. Society of Toxicology, 135(2):277-291, (2013).
REIF, D., M. T. MARTIN, S. TAN, K. A. HOUCK, R. JUDSON, A. M. RICHARD, T. B. KNUDSEN, D. J. DIX, AND R. J. KAVLOCK. Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(12):2-8, (2010).
KNIGHT, A. W., S. LITTLE, K. A. HOUCK, D. J. DIX, R. JUDSON, A. M. RICHARD, N. MCCARROLL, G. AKERMAN, C. YANG, L. BIRRELL, AND R. M. WALMSLEY. Evaluation of High-throughput Genotoxicity Assays Used in Profiling the US EPA ToxCast Chemicals. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, 55(2):188-99, (2009).
COHEN-HUBAL, E. A., A. M. RICHARD, I. A. SHAH, J. GALLAGHER, R. J. KAVLOCK, J. N. BLANCATO, AND S. W. EDWARDS. Exposure Science and the US EPA National Center for Computational Toxicology. Journal of Exposure Science and Environmental Epidemiology . Nature Publishing Group, London, Uk, 20(3):231-236, (2010).
MAHADEVAN, B., R. D. SNYDER, M. D. WATERS, R. D. BENZ, R. A. KEMPER, R. R. TICE, AND A. M. RICHARD. Genetic toxicology in the 21st century: Reflections and future directions. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. Wiley Liss, New York, NY, 52(5):339 - 354, (2011).
MARTIN, M. T., D. J. DIX, R. JUDSON, R. J. KAVLOCK, D. REIF, A. M. RICHARD, D. ROTROFF, S. ROMANOV, A. MEDVEDEV, N. POLTORATSKAYA, M. GAMBARIAN, M. MOESER, S. S. MAKAROV, AND K. A. HOUCK. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 23(3):578-90, (2010).
JUDSON, R., K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, H. M. MORTENSEN, D. REIF, D. ROTROFF, I. A. SHAH, A. M. RICHARD, AND D. J. DIX. In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(4):485-92, (2010).
DIX, D. J., K. A. HOUCK, R. JUDSON, N. KLEINSTREUER, T. B. KNUDSEN, M. T. MARTIN, D. REIF, A. M. RICHARD, I. A. SHAH, N. SIPES, AND R. J. KAVLOCK. Incorporating Biological, Chemical and Toxicological Knowledge into Predictive Models of Toxicity: Letter to the Editor. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 130(2):440-441, (2012).
WETMORE, B. A., J. F. WAMBAUGH, S. S. FERGUSON, M. A. SOCHASKI, D. M. ROTROFF, K. FREEMAN, H. J. CLEWELL III, D. J. DIX, M. E. ANDERSEN, K. A. HOUCK, B. ALLEN, R. S. JUDSON, R. SINGH, R. J. KAVLOCK, A. M. RICHARD, AND R. S. THOMAS. Integration of Dosimetry, Exposure and High-Throughput Screening Data in Chemical Toxicity Assessment. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 125(1):157-174, (2012).
JUDSON, R., R. J. KAVLOCK, M. T. MARTIN, D. REIF, K. A. HOUCK, T. B. KNUDSEN, A. M. RICHARD, R. R. TICE, M. WHELAN, M. XIA, R. HUANG, C. P. AUSTIN, G. P. DASTON, T. HARTUNG, J. R. FOWLE III, W. WOOGE, W. TONG, AND D. J. DIX. Perspectives on Validation of High-Throughput Assays Supporting 21st Century Toxicity Testing. Sonja von Aulock (ed.), ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 30(1/13):51-66, (2013).
Kleinstreuer, N., J. Yang, E. Berg, T. Knudsen, A. Richard, M. Martin, D. Reif, R. Judson, M. Polokoff, D. Dix, R. Kavlock, AND K. Houck. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nature Biotechnology. Elsevier Science, New York, NY, 32(6):583-591, (2014).
Benfenati, E., R. Benigni, D. M. Demarini, C. Helma, D. Kirkland, T. M. Martin, P. Mazzatorta, G. Ouedraogo-Arras, A. M. RICHARD, B. Schilter, W. G. Schoonen, R. D. Snyder, AND C. Yang. Predictive Models for Carcinogenicity and Mutagenicity: Frameworks,State-of-the-Art, and Perspectives. Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis Reviews. Taylor & Francis Group, London, Uk, 27(2):57-90, (2009).
Sipes, N., M. Martin, P. Kothiya, D. Reif, R. Judson, A. Richard, K. Houck, D. Dix, R. Kavlock, AND T. Knudsen. Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 26:878−895, (2013).
Attene-Ramos, M., R. Huang, S. Michael, K. Witt, A. Richard, R. Tice, A. Simeonov, C. Austin, AND M. Xia. Profiling of the Tox21 Chemical Collection for Mitochondrial Function: I. Compounds that Decrease Mitochondrial Membrane Potential. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 123(1):49-56, (2015).
Cherkasov, A., E. Muratov, D. Fourches, A. Varnek, I. Baskin, M. Cronin, J. Dearden, P. Gramatica, Y. Martin, R. Todeschini, V. Consonni, V. E. Kuzmin, R. Cramer, R. Benigni, C. Yang, J. Rathman, L. Terfloth, J. Gasteiger, A. Richard, AND A. Tropsha. QSAR Modeling: Where Have You Been? Where Are You Going To?. JOURNAL OF MEDICINAL CHEMISTRY. American Chemical Society, Washington, DC, 57(12):4977–5010, (2013).


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