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Records 1 to 25 of 41
KLEINSTREUER, N., D. J. DIX, M. ROUNTREE, N. BAKER, N. SIPES, D. REIF, R. SPENCER, AND T. B. KNUDSEN. A Computational Model Predicting Disruption of Blood Vessel Development. Shayn M.Pierce (ed.), PLoS Computational Biology. Public Library of Science, San Francisco, CA, 9(4):1-20, (2013).
BASKETTER, D. A., H. J. CLEWELL, I. KIMBER, A. ROSSI, B. BLAAUBOER, R. BURRIER, M. DANESHIAN, C. ESKES, A. GOLDBERG, N. HASIWA, S. HOFFMANN, J. JAWORSKA, T. B. KNUDSEN, R. LANDSIEDEL, M. LEIST, P. LOCKE, G. MAXWELL, J. MCKIM, E. A. MCVEY, G. OUEDRAOGO, G. PATLEWICZ, O. PELKONEN, E. ROGGEN, C. ROVIDA, I. RUHDEL, M. SCHWARZ, A. SCHEPKY, G. SCHOETERS, N. SKINNER, K. TRENTZ, M. TURNER, P. VANPARYS, J. YAGER, J. ZURLO, AND T. HARTUNG. A Roadmap for the Development of Alternative (Non-Animal) Methods for Systemic Toxicity Testing. SONJA von AULOCK, Editor in chief (ed.), ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 1(29):1-91, (2012).
KNUDSEN, T. B., K. A. HOUCK, N. SIPES, A. V. SINGH, R. JUDSON, M. T. MARTIN, A. WEISSMAN, N. KLEINSTREUER, H. M. MORTENSEN, D. REIF, J. R. RABINOWITZ, R. W. SETZER, A. M. RICHARD, D. J. DIX, AND R. J. KAVLOCK. Activity profiles of 309 ToxCastâ„¢ chemicals evaluated across 292 biochemical targets. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 282(1-2):1-15, (2011).
JUDSON, R., M. T. MARTIN, D. REIF, K. A. HOUCK, T. B. KNUDSEN, D. ROTROFF, M. XIA, S. SAKAMURU, R. HUANG, P. SHINN, C. P. AUSTIN, R. J. KAVLOCK, AND D. J. DIX. Analysis of Eight Oil Spill Dispersants Using Rapid, In Vitro Tests for Endocrine and Other Biological Activity. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 44(15):5979-5985, (2010).
Leist, M., N. Hasiwa, C. Rovida, M. Daneshian, D. Basketter, I. Kimber, H. Clewell, T. Gocht, A. Goldberg, F. Busquet, A. Rossi, M. Schwarz, M. Stephens, R. Taalman, T. Knudsen, J. McKim, G. Harris, D. Pamies, AND T. Hartung. Consensus report on the future of animal-free systemic toxicity testing. ALTEX. Society ALTEX Edition, Kuesnacht, Switzerland, 31(3):341-356, (2014).
KNUDSEN, T. B., R. J. KAVLOCK, G. P. DASTON, D. B. STEDMAN, M. HIXON, AND J. KIM. Developmental toxicity testing for safety assessment: new approaches and technologies. BIRTH DEFECTS RESEARCH PART B: DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY. John Wiley & Sons, Inc, Hoboken, NJ, 92(5):413-420, (2011).
GREEN, M. L., A. V. SINGH, L. RUEST, MICHELE M. PISANO, R. A. PROUGH, AND T. B. KNUDSEN. Differential programming of p53-deficient embryonic cells during rotenone block. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 290(1):31-41, (2011).
KNUDSEN, T. B. AND N. C. KLEINSTREUER. Disruption of Embryonic Vascular Development in Predictive Toxicology. Anthony M. DeLise (Guest Editor) (ed.), Birth Defects Research, Part C: Embryo Today: Reviews. John Wiley & Sons, Ltd., Indianapolis, IN, 93(4):312-323, (2011).
MARTIN, M. T., T. B. KNUDSEN, R. JUDSON, R. J. KAVLOCK, AND D. J. DIX. Economic benefits of using adaptive predictive models of reproductive toxicity in the context of a tiered testing program . Stephen A. Krawetz (Editor-in-Chief) (ed.), Systems Biology in Reproductive Medicine. Informa Healthcare USA, New York, NY, 58(1):3-9, (2012).
REIF, D., M. T. MARTIN, S. TAN, K. A. HOUCK, R. JUDSON, A. M. RICHARD, T. B. KNUDSEN, D. J. DIX, AND R. J. KAVLOCK. Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(12):2-8, (2010).
KLEINSTREUER, N. C., R. S. JUDSON, D. M. REIF, N. S. SIPES, A. V. SINGH, K. J. CHANDLER, R. DEWOSKIN, D. J. DIX, R. J. KAVLOCK, AND T. B. KNUDSEN. Environmental Impact on Vascular Development Predicted by High Throughput Screening. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(11):1596-1603, (2011).
JUDSON, R., R. J. KAVLOCK, R. W. SETZER, E. A. COHEN-HUBAL, M. T. MARTIN, T. B. KNUDSEN, K. A. HOUCK, R. S. THOMAS, B. A. WETMORE, AND D. J. DIX. Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 24(4):451-462, (2011).
Knudsen, T., D. Keller, M. Sander, E. Carney, N. Doerrer, D. Eaton, S. Fitzpatrick, K. Hastings, D. Mendric, R. Tice, P. Watkins, AND M. Whelan. FORUM - FutureTox II: In vitro Data and In Silico Models forPredictive Toxicology. TOXICOLOGICAL SCIENCES. Society of Toxicology, 143(2):256–267, (2015).
Datta, S., D. Turner, R. Singh, L. B. Ruest, W. Pierce, AND T. B. KNUDSEN. Fetal alcohol syndrome (FAS) in C57BL/6 mice detected through proteomics screening of the amniotic fluid. BIRTH DEFECTS RESEARCH PART A: CLINICAL AND MOLECULAR TERATOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 82(4):177-186, (2008).
Ema, M., R. Ise, H. Kato, S. Oneda, A. Hirose, M. Hirata-Koizumi, A. V. SINGH, T. B. KNUDSEN, AND T. Ihara. Fetal malformations and early embryonic gene expression response in cynomolgus monkeys maternally exposed to thalidomide. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 29(1):49-56, (2010).
WAMBAUGH, J. F., R. W. SETZER, D. REIF, S. GANGWAL, J. MITCHELLBLACKWOOD, J. A. ARNOT, O. JOLIET, A. FRAME, J. R. RABINOWITZ, T. B. KNUDSEN, R. S. JUDSON, P. P. EGEGHY, D. A. VALLERO, AND E. A. COHEN HUBAL. High-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project . Jerald Schnoor (ed.), ENVIRONMENTAL SCIENCE AND TECHNOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, 47(15):8479-8488, (2013).
Hao, R., M. Bondesson, A. Singh, A. Riu, C. McCollum, Thomas B. Knudsen, D. Gorelick, AND J. Gustafsson. Identification of Estrogen Target Genes during Zebrafish Embryonic Development through Transcriptomic Analysis. PLoS ONE . Public Library of Science, San Francisco, CA, 8(11):1-18, (2013).
KLEINSTREUER, N. C., A. M. SMITH, P. R. WEST, K. CONARD, B. FONTAINE, A. M. WEIR-HAUPTMAN, J. PALMER, T. B. KNUDSEN, D. J. DIX, E. L. DONLEY, AND G. G. CEZAR. Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics . TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier Science Inc., Burlington, MA, Online:1-10, (2011).
Tal, T., C. McCollum, P. Harris, J. Olin, N. Kleinstreuer, C. Wood, C. Hans, S. Shah, F. Merchant, M. Bondesson, T. Knudsen, S. Padilla, AND M. Hemmer. Immediate and long-term consequences of vascular toxicity during zebrafish development. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 48:51-61, (2014).
JUDSON, R., K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, H. M. MORTENSEN, D. REIF, D. ROTROFF, I. A. SHAH, A. M. RICHARD, AND D. J. DIX. In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 118(4):485-92, (2010).
Judson, R., K. Houck, M. Martin, T. Knudsen, R. Thomas, N. Sipes, I. Shah, J. Wambaugh, AND K. Crofton. In Vitro and Modeling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Program. BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. Blackwell Publishing, Malden, MA, 115(1):69-76, (2014).
KLEINSTREUER, N., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, K. B. PAUL, D. REIF, K. M. CROFTON, K. HAMILTON, R. HUNTER, I. A. SHAH, AND R. JUDSON. In vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, Epub(Advance Access):1-44, (2012).
DIX, D. J., K. A. HOUCK, R. JUDSON, N. KLEINSTREUER, T. B. KNUDSEN, M. T. MARTIN, D. REIF, A. M. RICHARD, I. A. SHAH, N. SIPES, AND R. J. KAVLOCK. Incorporating Biological, Chemical and Toxicological Knowledge into Predictive Models of Toxicity: Letter to the Editor. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 130(2):440-441, (2012).
Judson, Richard S., F. Magpantay, V. Chickarmane, C. Haskell, N. Tania, J. Taylor, M. Xia, R. Huang, D. Rotroff, D. Filer, K. Houck, M. Martin, N. Sipes, A. Richard, K. Mansouri, W. Setzer, T. Knudsen, K. Crofton, AND R. Thomas. Integrated Model of Chemical Perturbations of a Biological PathwayUsing 18 In Vitro High Throughput Screening Assays for the Estrogen Receptor. TOXICOLOGICAL SCIENCES. Society of Toxicology, :1-42, (2015).
LUIJTEN, M., A. V. SINGH, C. A. BASTIAN, A. WESTERMAN, M. M. PISANO, J. L. PENNINGS, A. VERHOEF, M. L. GREEN, A. H. PIERSMA, A. de VRIES, AND T. B. KNUDSEN. Lasting Effects on Body Weight and Mammary Gland Gene Expression in Female Mice upon Early Life Exposure to n-3 but Not n-6 High-Fat Diets. PLoS ONE . Public Library of Science, San Francisco, CA, 8(2):1-11, (2013).


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