Jump to main content or area navigation.

Contact Us

Computational Toxicology Research

Key Links
CompTox Home Basic Information Organization EPA Exposure Research Research Projects Chemical Databases ToxCast Stakeholder Events EPA Chemical Safety Research Research Publications Scientific Reviews Communities of Practice ToxCast Data Challenges Staff Profiles CompTox Partners Jobs and Opportunities
Records 1 to 14 of 14
KLEINSTREUER, N., D. J. DIX, M. ROUNTREE, N. BAKER, N. SIPES, D. REIF, R. SPENCER, AND T. B. KNUDSEN. A Computational Model Predicting Disruption of Blood Vessel Development. Shayn M.Pierce (ed.), PLoS Computational Biology. Public Library of Science, San Francisco, CA, 9(4):1-20, (2013).
KNUDSEN, T. B., K. A. HOUCK, N. SIPES, A. V. SINGH, R. JUDSON, M. T. MARTIN, A. WEISSMAN, N. KLEINSTREUER, H. M. MORTENSEN, D. REIF, J. R. RABINOWITZ, R. W. SETZER, A. M. RICHARD, D. J. DIX, AND R. J. KAVLOCK. Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets. TOXICOLOGY. Elsevier Ireland Limited, Limerick, Ireland, 282(1-2):1-15, (2011).
KNUDSEN, T. B. AND N. C. KLEINSTREUER. Disruption of Embryonic Vascular Development in Predictive Toxicology. Anthony M. DeLise (Guest Editor) (ed.), Birth Defects Research, Part C: Embryo Today: Reviews. John Wiley & Sons, Ltd., Indianapolis, IN, 93(4):312-323, (2011).
KLEINSTREUER, N. C., R. S. JUDSON, D. M. REIF, N. S. SIPES, A. V. SINGH, K. J. CHANDLER, R. DEWOSKIN, D. J. DIX, R. J. KAVLOCK, AND T. B. KNUDSEN. Environmental Impact on Vascular Development Predicted by High Throughput Screening. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 119(11):1596-1603, (2011).
CHANDLER, K. J., M. BARRIER, S. C. JEFFAY, H. P. NICHOLS, N. KLEINSTREUER, A. Singh, D. REIF, N. SIPES, R. JUDSON, D. J. DIX, R. J. KAVLOCK, E. S. HUNTER, AND T. Knudsen. Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay. PLoS ONE . Public Library of Science, San Francisco, CA, 6(6):e1840, (2011).
KLEINSTREUER, N. C., A. M. SMITH, P. R. WEST, K. CONARD, B. FONTAINE, A. M. WEIR-HAUPTMAN, J. PALMER, T. B. KNUDSEN, D. J. DIX, E. L. DONLEY, AND G. G. CEZAR. Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics . TOXICOLOGY AND APPLIED PHARMACOLOGY. Elsevier Science Inc., Burlington, MA, Online:1-10, (2011).
Tal, T., C. McCollum, P. Harris, J. Olin, N. Kleinstreuer, C. Wood, C. Hans, S. Shah, F. Merchant, M. Bondesson, T. Knudsen, S. Padilla, AND M. Hemmer. Immediate and long-term consequences of vascular toxicity during zebrafish development. REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 48:51-61, (2014).
KLEINSTREUER, N., D. J. DIX, K. A. HOUCK, R. J. KAVLOCK, T. B. KNUDSEN, M. T. MARTIN, K. B. PAUL, D. REIF, K. M. CROFTON, K. HAMILTON, R. HUNTER, I. A. SHAH, AND R. JUDSON. In vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, Epub(Advance Access):1-44, (2012).
DIX, D. J., K. A. HOUCK, R. JUDSON, N. KLEINSTREUER, T. B. KNUDSEN, M. T. MARTIN, D. REIF, A. M. RICHARD, I. A. SHAH, N. SIPES, AND R. J. KAVLOCK. Incorporating Biological, Chemical and Toxicological Knowledge into Predictive Models of Toxicity: Letter to the Editor. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 130(2):440-441, (2012).
Kleinstreuer, N., J. Yang, E. Berg, T. Knudsen, A. Richard, M. Martin, D. Reif, R. Judson, M. Polokoff, D. Dix, R. Kavlock, AND K. Houck. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nature Biotechnology. Elsevier Science, New York, NY, 32(6):583-591, (2014).
SIPES, N. S., M. T. MARTIN, D. M. REIF, N. C. KLEINSTREUER, R. S. JUDSON, A. V. SINGH, K. J. CHANDLER, D. J. DIX, R. J. KAVLOCK, AND T. B. KNUDSEN. Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data. TOXICOLOGICAL SCIENCES. Oxford University Press, Cary, NC, 124(1):109-127, (2011).
Browne, P., R. Judson, W. Casey, N. Kleinstreuer, AND R. Thomas. SCREENING CHEMICALS FOR ESTROGEN RECEPTOR BIOACTIVITY USING A COMPUTATIONAL MODEL. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 49(14):8804-8814, (2015).
Kavlock, R., K. Chandler, K. Houck, S. Hunter, R. Judson, N. Kleinstreuer, T. Knudsen, M. Martin, S. Padilla, D. Reif, A. Richard, D. Rotroff, N. Sipes, AND D. Dix. Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, 25(7):1287-1302, (2012).
PADILLA, S. J., D. CORUM, B. K. PADNOS, D. L. HUNTER, A. BEAM, K. A. HOUCK, N. SIPES, N. KLEINSTREUER, T. B. KNUDSEN, D. J. DIX, AND D. M. REIF. Zebrafish Developmental Screening of the ToxCast™ Phase I Chemical Library . REPRODUCTIVE TOXICOLOGY. Elsevier Science Ltd, New York, NY, 33(2):174-187, (2012).


Jump to main content.