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  • Organization = [ORD-NHSRC]
  • Keyword = 'Microbial risk' OR 'microbial risk assessment' OR 'dose response' OR 'dose response' OR 'exposure assessment'.
Records 1 to 25 of 39

2020
Physiological responses to a single low-dose of Bacillus anthracis spores in the rabbit model of inhalational anthrax
(JOURNAL) [Published : Jun 11, 2020]
Journal Article--Bacillus anthracis, the causative agent of inhalation anthrax, is one of the most highly studied biological threat agents, yet consensus is still lacking on an appropriate dose-response relationship to describe human health effects from low doses and multiple exp...
2019
Chlorine Exposure During a Biological Decontamination Study in a Mock Subway Tunnel
(JOURNAL) [Published : Jul 12, 2019]
The Underground Transport Restoration (UTR) Operational Technology Demonstration (OTD) was a full-scale study focused on remediation of a subway system after contamination with a Bacillus anthracis (Ba) surrogate (Bacillus atrophaeus, subspecies globigii [Bg]). The study involved...
Radiological Emergency: Exposure Assessment of Livestock Carcass Management
(PUBLISHED REPORT) [Published : Jun 06, 2019]
The potential exposures and exposure pathways were compared for various options to support decision-making in the event of a radiological emergency to provide an in-depth evaluation based on understanding of ionizing radiation and radiation exposure, conceptual models of potentia...
2018
Application of Quantitative Dose-Response Data in Risk Assessment and the Incorporation of High-Throughput Data
(BOOK CHAPTER) [Published : Mar 01, 2018]
Book Chapter—This invited contribution is the concluding chapter of this important reference book. It brings together concepts discussed in preceding chapters so that the reader understands how to quantify and apply reliable findings in health risk assessment decisions.
Exposure Assessment During a Chemical Attack: Livestock Carcass Management
(PUBLISHED REPORT) [Published : Sep 17, 2018]
Report--Exposure estimates were performed to rank the various livestock carcass management options relative to one another for a hypothetical site and mortality scenario from a potential chemical attack or chemical contamination emergencies. A tiered approach was effective to ran...
Exposure Assessment of Livestock Carcass Management Options During a Foreign Animal Disease Outbreak
(PUBLISHED REPORT) [Published : Aug 21, 2018]
Report—Exposure estimates were performed to rank the various livestock carcass management options relative to one another for a hypothetical site and mortality scenario from a potential biological incident. Assessment included an ordinal scale ranking (ranking of individual condi...
Exposure Pathways to High-Consequence Pathogens in the Wastewater Collection and Treatment Systems
(PUBLISHED REPORT) [Published : Aug 01, 2018]
Report--Provides information and a screening tool to perform an exposure assessment for emerging pathogens in wastewater systems
Risk Assessment Approaches for Acute and Short-Duration Exposures. HS7.53.07
(PRESENTATION) [Presented : Apr 26, 2018]
This presentation will support a platform talk that describes the application of toxicity findings to assess the risk of chemical exposures. it will focus on inhalation exposures to irritant chemicals, with respect to developing and quantifying the health impact of adverse effec...
2017
2016
Review of Bacillus anthracis Dose Response Data for Human Health Risk Assessment
(PUBLISHED REPORT) [Published : Jun 10, 2016]
Interest in low-dose dose-response relationships for Bacillus anthracis exposure can be traced to data gaps made apparent during the civilian response to the 2001 anthrax letter event. This report conducts a systematic review of Bacillus anthracis dose-response data that can be u...
2015
2014
2012
Review of Bacillus anthracis (Anthrax) studies for dose-response modeling to estimate risk
(SUMMARY) [Published : Oct 31, 2012]
This technical brief identifies current challenges in the development of a Bacillus anthracis dose-response relationship specifically for low dose exposures, summarizes available dose-response data sets for inhalation exposures in commonly used animal models and observational dat...
2011
Acute Low Dose Bacillus anthracis Ames Inhalation Exposures in the Rabbit
(PUBLISHED REPORT) [Published : Sep 27, 2011]
Report
2010
Pathogen Information Catalogue (PI CAT) Tool
(DATA/SOFTWARE) [Published : Feb 21, 2010]
Access Database tool for microbial dose-response data sets to perform microbial risk assessments for biological threat agents.