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This Facilitator Manual provides the practical steps necessary for an agency or organization to implement a multi-session, participatory workshop for municipalities to engage their communities in the development of stormwater funding solutions. The Manual is a paired resource wit...

Microbiota regulate important physiologic processes during early host development. They also biotransform xenobiotics and serve as key intermediaries for chemical exposure. Antimicrobial agents in the environment may disrupt these complex interactions and alter key metabolic func...

Adverse intrauterine environments have been associated with increased risk of later cardiovascular disease and hypertension. In an animal model using diverse developmental toxicants, we measured blood pressure (BP), renal nephron endowment, renal glucocorticoid receptor (GR) gene...

Perfluorononanoic acid (PFNA) is a ubiquitous and persistent environmental contaminant. Although its levels in the environment and in humans are lower than those of perfluorooctane sulfonate(PFOS) or perfluorooctanoic acid (PFOA), a steady trend of increases in the general popula...

Oil spill chemical response agents, including those that function as dispersants, solidifiers, surface washers, and surface collectors, are used globally to combat oil spills by changing the physical structure of the oil in the spill to facilitate breakdown and biodegradation. A ...

The National Lakes Assessment 2017: A Collaborative Survey of Lakes in the United States presents the results of a second evaluation of the lakes in the United States. This report is part of the National Aquatic Resource Surveys, a series of statistically based surveys designed t...

Wildland fire smoke contains hazardous levels of fine particulate matter (PM2.5), a pollutant shown to adversely effect health. Estimating fire attributable PM2.5 concentrations is key to quantifying the impact on air quality and subsequent health burden. This is a challenging pr...

Federal estuary management programs have widely used ecosystem services concepts to frame management issues and communicate with stakeholders. However, widespread implementation of ecosystem services assessments in estuary management has been limited due to concerns of being too ...

Coastal towns and cities are looking for more sustainable ways to build on local assets to maintain or improve their quality of life. Access to more locally relevant information is needed to better assist communities in making progress toward their goals, especially in smaller co...

The skin is an essential organ because it protects the internal organs from the outside environment, maintains body water, regulates temperature, and provides overall support to the body. The skin has two main elements, the outer epidermis and the underlying dermis. The cells of ...

Estuaries provide a suite of ecosystem services to people but are also under heavy stress from human development including excess nutrient loading and alterations in benthic habitat that affect nutrient cycling. Here we examine the interaction of two important and common ecosyste...

Susceptibility to xenobiotic exposures is variable. One factor that might account for this is the microbiome, which encompasses all microorganisms, their encoded genes, and associated functions that colonize a host organism. Microbiota harbor the capacity to affect the toxicokine...

The International Workshop on Genotoxicity Testing (IWGT) meets every four years to seek consensus on difficult or conflicting approaches to genotoxicity testing based upon experience, available data, and analysis techniques. At the 2017 IWGT meeting in Tokyo, one working group a...

There are several known adverse health effects in the skin following overexposure to ultraviolet (UV) light from the sun. Acute effects from UV light overexposure include erythema, immunosuppression and burns; chronic effects include photoaging and cancer. Occurrence of skin canc...

Physiologically-based pharmacokinetic (PBPK) models are a well-accepted tool used by regulatory agencies for multiple risk assessment applications. These applications include exposure route extrapolation, exposure scenario extrapolation, and cross-species extrapolation. All of th...

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Natural capital accounting is a method of assessing the contribution of ecosystems to the economy, making the links between natural and economic systems more clear. While the System of Environmental-Economic Accounts&rsquo; Central Framework (developed by the U.N. and other inter...

The nation&rsquo;s economic accounts provide objective, regular, and standardized information routinely relied upon by public and private decision makers. But they are incomplete. The U.S. and many other nations currently do not account for the natural capital &mdash; such as the...

The EPA&rsquo;s ACE research program and Office of Air Quality Planning and Standards (OAQPS) co-sponsored a &ldquo;Wildfire Smoke Health Risk Management and Communication Workshop&rdquo; with the goal to identify opportunities for research and technological solutions that could ...

Nanomaterials peculiar attributes are being explored for the benefits of the society; however, the widespread use of these materials are expected to contaminate the environment. For example, nanomaterials can reach the agricultural fields through the addition of sewage sludge (bi...

The overarching goal of USEPA’s Sustainable and Healthy Communities Research Program (SHCRP) is to inform and empower decision makers to equitably weigh and integrate human health, socio-economic, environmental, and ecological factors to foster sustainability in the built and nat...

Microcystins are the most common group of cyanobacterial hepatotoxins found in freshwater in the U.S., and microcystin-LR (MCLR) is one of the most common forms. Understanding its spectrum of effects and dose-response relationships depends on consistent experimental results which...

<br>This workshop will provide an up-to-date overview on key issues related to cancer risk assessment of arsenic: carcinogenic mechanisms; application of mechanistic information to risk assessment models; and the development of the MCL for arsenic in drinking water. The two prese...

Transcriptomic biomarkers can be used to inform molecular initiating and key events involved in a toxicant&rsquo;s mode of action. To address the limited approaches available for identifying epigenotoxicants, we developed and assessed a transcriptomic biomarker of histone deacety...

Understanding the effects of human activity on coral reef ecosystems requires knowing what characteristics constitute a high quality coral reef and identifying measurable criteria. The Biological Condition Gradient (BCG) is a conceptual model that describes how biological attribu...