Jump to main content or area navigation.

Contact Us

EPA's Report on the Environment: External Review Draft

Infectious Diseases Associated with Environmental Exposures or Conditions



Note to reviewers of this draft revised ROE: This indicator reflects data through 2009. EPA anticipates updating this indicator in 2014.








  • Learn more about how to use this interactive exhibit
  • Save the complete indicator as a printer-friendly PDF
  • Download this image
  • Download data for this exhibit

Choose a disease from the list. Hover your mouse over the display to reveal data.



  • Learn more about how to use this interactive exhibit
  • Save the complete indicator as a printer-friendly PDF
  • Download this image
  • Download data for this exhibit

Choose a disease from the list. Hover your mouse over the display to reveal data.

  • Learn more about how to use this interactive exhibit
  • Save the complete indicator as a printer-friendly PDF
  • Download this image
  • Download data for this exhibit

Hover your mouse over the display to reveal data.

Introduction

Infectious diseases are human illnesses caused by viruses, bacteria, parasites, fungi, and other microbes. They can be spread by direct contact with an infected person or animal, through ingestion of contaminated food or water, by insects like mosquitoes or ticks (disease vectors), or by contact with contaminated surroundings such as through touching animal droppings or breathing in contaminated air. Demographic and environmental factors such as population growth, increased urbanization, and alteration of habitats of disease-carrying insects and animals (e.g., irrigation, deforestation) may promote the spread of infectious diseases (CDC, 1998a). The three broad infectious disease categories included here are those whose appearance and spread may be influenced to some extent by environmental conditions and change. They include gastrointestinal (GI) diseases, arthropod-borne diseases, and legionellosis.

  • Gastrointestinal diseases. Eight notifiable GI diseases caused by microorganisms are discussed below: cholera, cryptosporidiosis, shiga toxin-producing Escherichia coli (E. coli) (STEC), giardiasis, hepatitis A, salmonellosis, shigellosis, and typhoid fever. The major environmental source of gastrointestinal illness is water or food that is contaminated with pathogenic microorganisms. The primary means of transmission for these eight diseases is through ingestion of contaminated food/water or through contact with and accidental ingestion of fecal matter (CDC, 2005a).
  • Arthropod-borne diseases. Three arthropod-borne diseases are included: Lyme disease (transmission of Borrelia burgdorferi by ticks), Rocky Mountain spotted fever (transmission of Rickettsia rickettsii by ticks), and West Nile virus (transmitted by mosquitoes). Certain ticks and mosquitoes (arthropods) can carry bacteria and viruses that cause disease in humans. The arthropods acquire the bacteria or viruses when they bite an infected mammal or bird. Some studies indicate that spread of vector-borne disease may be influenced by land use and/or other environmental change (CDC, 2004). In recent years, both Lyme disease and West Nile virus have spread across the U.S. (CDC, 1993, 2000, 2004). Surveillance for Lyme disease was initiated by the Centers for Disease Control and Prevention (CDC) in 1982 (CDC, 1993).
  • Legionellosis. Legionellosis, or Legionnaires’ disease, is a serious and sometimes fatal form of pneumonia. It is caused by Legionella bacteria, which are found naturally in the environment and thrive in warm water and warm damp places. They are commonly found in lakes, rivers, creeks, hot springs, and other bodies of water. This bacterium has been associated with outbreaks in the U.S. linked to poorly maintained artificial water systems (e.g., air conditioning and industrial cooling systems) and air ventilation systems. Infection results from inhalation of contaminated water sprays or mists (CDC, 2011a).

This indicator reflects occurrence of these notifiable diseases as reported by health departments to the National Notifiable Diseases Surveillance System (NNDSS). A notifiable disease is one for which regular, frequent, and timely information regarding individual cases is considered necessary for the prevention and control of the disease (CDC, 2005b). Data are collected by all 50 states, five territories, New York City, and the District of Columbia, based on a list of recommended nationally notifiable infectious diseases, and compiled nationally. The temporal coverage of the data varies by disease. The number of states reporting may also vary. For example, in 1995, when cryptosporidiosis was first nationally reported, only 27 states reported; 45 states reported this disease by 1997.

What the Data Show

Gastrointestinal Diseases

Exhibit 1 presents the number of reported cases for each of the eight notifiable GI diseases from 1995-2009. In comparison to the other GI diseases, the number of newly identified cholera cases reported each year is low. From 1995 to 2009, just 112 laboratory-confirmed cases of cholera were reported to CDC, with 10 cases being reported in 2009, the most current reporting year. The number of newly identified cases of typhoid fever was relatively stable from 1995 to 2006, ranging between a low of 321 cases in 2002 and a high of 396 cases in 1996. There was a notable increase in the number of cases of typhoid fever reported in 2007 (434 cases) and 2008 (449 cases). In 2009, there were 397 cases of typhoid fever, which is more consistent with the period between 1995 and 2006.  Hepatitis A has continued to decline, with 31,582 cases reported in 1995 compared to 1,987 cases in 2009. The increasing trend of reported cryptosporidiosis cases between 2005 (5,659) and 2007 (11,170) was reversed in 2008 and 2009 with 9,113 and 7,654 cases being reported, respectively; this is still well above the number of cases reported between 1995 and 2004.  It remains unclear whether the greater number of case reports between 2005 and 2009 reflects changes in reporting patterns and diagnostic testing practices or a real change in infection transmission. For example, the increase in 2005 (and possibly 2007) was attributable primarily to outbreak-related case reporting. However, increased testing for Cryptosporidium following the introduction of nitazoxanide (2002-2004), the first licensed treatment for the disease, also may have led to a possible increase in subsequent case reporting (CDC, 2008). In 2009, 15,931 cases of shigellosis were reported, which reverses a two year increase in the number of cases. A slight, overall decline in the number of cases was observed for giardiasis over the 8 years of reporting data available. Similarly, the number of reported cases of E. coli (presented in Exhibit 1 as shiga toxin-producing E. coli, or STEC) dropped in 2009 (4,643) compared to those reported in 2008 (5,309), which was the highest number of cases during the reporting period.

Arthropod-Borne Diseases

Exhibit 2 presents the number of reported cases for three arthropod-borne diseases. Lyme disease is the most commonly reported arthropod-borne disease in the U.S., with 38,468 cases reported in 2009, a 9 percent increase from 2008 (35,198 cases) and nearly double the number reported in 2006 (19,931 cases). CDC began surveillance of Rocky Mountain spotted fever in 1970. The number of new cases of Rocky Mountain spotted fever reported from 1995 to 2008 has generally been increasing, ranging between a low of 365 cases in 1998 and a high of 2,563 cases in 2008. In 2009, however, a decrease was observed with 1,815 cases reported. Cases of West Nile virus were first documented in the U.S. in 1999. West Nile virus became nationally reportable in 2002, and the number of reported cases rose from 2,840 in 2002 to 2,866 in 2003. Between 2004 and 2007 the number of reported cases remained relatively stable, ranging from 1,142 reported cases in 2004 to 1,495 reported cases in 2006. In 2009, 386 cases of West Nile virus were reported, representing a continued notable decrease from 2007 (1,227 cases) and 2008 (689 cases).

Legionellosis

Exhibit 3 presents the number of reported cases of legionellosis within the U.S. population from 1995 to 2009. From 1995 to 2002, the number of new cases of legionellosis was relatively stable, ranging from a low of 1,108 cases in 1999 to 1,355 cases in 1998. However, an increase in the number of new cases was reported since 2003, with the highest number reported in 2009 (3,522 cases).

Limitations

  • State health departments report cases of notifiable diseases to CDC; reporting policies (and compliance with those policies) can vary by disease or reporting jurisdiction.
  • Disease reporting likely underestimates the actual number of cases for a given time period because reporting nationally notifiable diseases to CDC is voluntary. Additionally, the completeness of reporting likely varies by disease. The degree of completeness of data reporting is influenced by many factors such as the diagnostic facilities available, the control measures in effect, public awareness of a specific disease, and the interests, resources, and priorities of state and local officials responsible for disease control and public health surveillance (CDC, 2011b).
  • Factors such as changes in case definitions for public health surveillance, introduction of new diagnostic tests, or discovery of new disease entities can cause changes in disease reporting that are independent of the true incidence of disease (CDC, 2004).
  • Prior to 2001, shiga toxin-producing Escherichia coli (STEC) represents E. coli O157:H7, which was the only serotype that was nationally notifiable. From 2001-2005, STEC represents the sum of the three nationally notifiable shiga toxin-positive E. coli forms (O157:H7, non-O157, and not serogrouped). As of 2006, serogrouped E. coli cases are no longer nationally notifiable; STEC represents the notifiable form. These differences in reporting should be considered when making cross-year comparisons.
  • Prior to 2005, only confirmed “neuroinvasive” cases of West Nile virus—the most severe form of the condition—were reported. Beginning in 2005, non-neuroinvasive domestic arboviral diseases for the six domestic arboviruses listed were added to the list of nationally notifiable diseases; these included West Nile fever, a non-neuroinvasive form of West Nile virus (CDC, 2007). In order to maintain reporting consistency, only neuroinvasive cases are presented for this indicator.

Data Sources

The data for this indicator were obtained from CDC annual reports that summarize data on nationally notifiable infectious diseases reported to CDC by state health agencies across the country (CDC, 1996, 1997, 1998b, 1999, 2001, 2002, 2003, 2004, 2005b, 2006, 2007, 2008, 2009, 2010, 2011b). Data are collected and compiled from reports sent by state health departments to the NNDSS, which is operated by CDC. The NNDSS is neither a single surveillance system nor a method of reporting. Certain NNDSS data are reported to CDC through separate surveillance information systems and through different reporting mechanisms; however, these data are aggregated and compiled for publication purposes (CDC, 2011b).

 

This page provides links to non-EPA websites that provide additional information about this topic. You will leave the EPA.gov domain, and EPA cannot attest to the accuracy of information on that non-EPA page. Providing links to a non-EPA website is not an endorsement of the other site or the information it contains by EPA or any of its employees. Also, be aware that the privacy protection provided on the EPA.gov domain (see Privacy and Security Notice) may not be available at the external link. Exit EPA Disclaimer

You will need the free Adobe Reader to view some of the files on this page. See EPA's PDF page to learn more.


Jump to main content.