Skip common site navigation and headers
United States Environmental Protection Agency
Exposure Research
Begin Hierarchical Links EPA Home > Research & Development > Exposure Research > Publications/Presentations > End Hierarchical Links

 

Longitudinal Study of Young Children's Exposures in Their Homes to Selected Pesticides, Phthalates, Brominated Flame Retardants, and Perfluorinated Chemicals (a Children's Environmental Exposure Research Study Cheers)

spacer
spacer
Abstract:The U.S. Environmental Protection Agency's (EPA) National Exposure Research Laboratory (NERL) is conducting a study of young children's exposures to chemicals in the home. The American Chemistry Council (ACC) is partnering with the EPA to enhance an existing EPA study of children's exposure to pesticides in residences by including additional measurements and data collection to evaluate the potential exposures of very young children to three classes of organic compounds that may be found in residences. The study, which will start in the fall of 2004, is a two-year longitudinal study in Jacksonville, Florida originally designed to measure the aggregate exposures for children 3 months to 3 years of age to current use indoor residential pesticides (primarily pyrethroids). Approximately 60 infants/toddlers will be enrolled in the study in two cohorts: (1) infants recruited into the study soon after birth, and, (2) children recruited into the study at approximately one year of age. Participant recruitment will be performed at Duval County Health Department clinics, local hospitals, and other child-friendly locations in the County. The study involves up to six visits during the two-year period during which measurements will be performed for all pathways and routes of exposure. Urine samples will be collected and analyzed for pesticide and phthalate metabolites by the Centers for Disease Control and Prevention, another partner in the study.

The ACC-funded enhancement to the study will allow the EPA to perform aggregate exposure estimates for the children in the existing study to a suite of phthalates. The exposures will be estimated using measurements of phthalates for all pathways and routes of exposure. Results of aggregate exposure estimates from the environmental and diet measurements will be compared to biomarker data from urine samples collected from the study participants. Additionally, using resources from the ACC, measurements will be made to evaluate the potential exposures of the children in the study to selected polybrominated diphenyl ethers (PBDEs) and to selected perfluorinated compounds in their residences. Although aggregate exposure estimates will not be performed for these two classes of compounds, data in the study will provide information on the potential magnitude of exposure and the temporal and spatial variability.

This study will provide critically needed data on very young children's exposures to chemicals in their homes. Data will be used to gain a better understanding of the factors affecting children's exposures, the impact of children's age and activities on their exposures, the important routes and pathways of exposures, and the use of biomarkers as indicators of exposure for pesticides and phthalates.

Although this work was reviewed by EPA and approved for publication, it may not necessarily reflect Agency policy.
spacer
Citation:Tulve, N. S., and R. C. Fortmann. Longitudinal Study of Young Children's Exposures in Their Homes to Selected Pesticides, Phthalates, Brominated Flame Retardants, and Perfluorinated Chemicals (a Children's Environmental Exposure Research Study Cheers). Presented at American Chemistry Council Peer Advisory Committee Meeting, Arlington, VA, October 6, 2004.
spacer
spacer
Contact: Liz Hope - (919) 541-2785 or hope.elizabeth@epa.gov
spacer
Division: Human Exposure & Atmospheric Sciences Division
spacer
Branch: Exposure Measurements & Analysis Branch
spacer
Product Type: Abstrct/Oral
spacer
Presented: 10/06/2004
spacer
spacer

 

ORD Home | Search EPA | Search NERL | Search EIMS | Contacts | Help

 
Begin Site Footer

EPA Home | Privacy and Security Notice | Contact Us

Last Updated on Monday, October 22, 2007
URL: http://cfpub.epa.gov