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Immunochemical Applications in Environmental Science

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Abstract: Immunochemical methods are based on selective antibodies combining with a particular target analyte or analyte group. The specific binding between antibody and analyte can be used to detect environmental contaminants in a variety of sample matrixes. Immunoassay methods provide cost-effective, sensitive, and selective analyses for many compounds of environmental and human health concern. Immunoaffinity chromatography methods have been integrated with chromatographic methods and are also being used as efficient sample preparations prior to immunochemical or instrumental detection. Immunosensors show promise in obtaining rapid online analyses. These and other advancements in immunochemical methods continue the expansion of their role from field screening methods to highly quantitative procedures that can be easily integrated into the environmental analytical laboratory.

The U.S. Environmental Protection Agency (EPA), through its Office of Research and Development (ORD), funded and collaborated in the research described here. It has been subjected to the Agency's peer review and has been approved as an EPA publication. Mention of trade names or commercial products does not constitute endorsement or recommendation by the EPA for use.
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Citation:Van Emon, J. M. Immunochemical Applications in Environmental Science. JOURNAL OF AOAC INTERNATIONAL 84(1):125-133, (2001).
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Contact: Liz Hope - (919) 541-2785 or hope.elizabeth@epa.gov
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Division: Human Exposure & Atmospheric Sciences Division
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Branch: Human Expsoure Research Branch
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Product Type: Journal
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Published: 05/08/2001
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Related Entries:
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Bullet Item Field Analytical Methods: Advanced Field Monitoring Methods Development and Evaluation of New and Innovative Technologies That Support the Site Characterization and Monitoring Requirements of the Superfund Program.
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Last Updated on Monday, October 22, 2007
URL: http://cfpub.epa.gov