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The Association of Exposure to Particulate Matter and Related Air Pollutants With Specific Health Effects in Healthy Highway Patrol Officers

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Abstract:Estimated exposures to ambient respirable particulate matter (PM) and related co-pollutants have been statistically associated with mortality and morbidity in epidemiological studies conducted throughout the world. Although some subpopulations (e.g., asthmatics; elderly, pulmonary-or cardiovascular-impaired) appear to be more susceptible to adverse health effects from these exposures, no specific causal agent or precise mechanisms underlying mortality or morbidity have been clearly identified. In an attempt to address this area of uncertainty, the National Exposure Research Laboratory (NERL) and the National Health and Environmental Effects Research Laboratory (NHEERL) successfully collaborated with the University of North Carolina at Chapel Hill and the North Carolina Highway Patrol to investigate the potential health effects of mobile source-related exposures on 9 healthy, non-smoking, North Carolina highway patrol officers. Troopers were monitored over a six week period to determine the association between specific mobile-source related air pollutants and changes in select health effect indicators. Troopers are potentially exposed to high levels of mobile source-related air pollutants because they spend a majority of each day traveling in cars on urban roads. Data has provided the first indication that in-vehicle related PM exposures might be associated with discrete changes in cardiovascular, immunological and other physiological measures in healthy adults. These findings may provide insight as to specific air pollutants (and sources) responsible for adverse health effects observed in sensitive subpopulations. This collaboration was shown to be beneficial and necessary, in that it utilized specific resources and talents of each collaborating organization's staff that otherwise would not have permitted the study to have been performed by a single organization.
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Citation:Williams, R. W., M. Riediker, L. S. Sheldon, R. B. Devlin, T. Griggs, P. A. Bromberg, L. Neas, M. Herbst, and W. Cascio. The Association of Exposure to Particulate Matter and Related Air Pollutants With Specific Health Effects in Healthy Highway Patrol Officers. Presented at Science Forum 2003, Washington, DC, May 5-7, 2003.
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Contact: Liz Hope - (919) 541-2785 or hope.elizabeth@epa.gov
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Division: Human Exposure & Atmospheric Sciences Division
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Branch: Exposure Measurements & Analysis Branch
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Product Type: Abstrct/Oral
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Presented: 05/06/2003
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Related Entries:
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Bullet Item Human Exposure Measurements of Air Toxics
spacer Relationship Reason:   A Project of the Product
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Last Updated on Monday, October 22, 2007
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