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Development of a Molecular Method to Identify the Merging Pathogen Hepatitis E in Water Samples

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Abstract:Hepatitis E virus (HEV) is an emerging pathogen that causes significant illness in the developing world. Like the hepatitis A virus, it is transmitted via the fecal-oral route and can cause short-term, acute hepatitis. In addition, hepatitis E has been found to cause a significant rate of mortality in pregnant women. Thus far, a hepatitis E outbreak has not been reported in the U. S. although a swine variant of the virus is common in Midwestern hogs. Since it will be important to identify the presence of this virus in the water supply, we have developed and are testing a reverse transcription-polymerase chain reaction (RT-PCR) method that should be able to identify all of the known HEV strains.
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Citation:Grimm, A. C., and G. S. Fout. Development of a Molecular Method to Identify the Merging Pathogen Hepatitis E in Water Samples. Presented at Fifthteenth Annual Scientific Symposium of the Ohio River Basin Consortium for Research and Education, Cincinnati, OH, October 20-22, 1999.
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Contact: Mary P. O'Bryant - (919)-541-4871 or obriant.mary@epa.gov
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Division: Microbiological & Chemical Exposure Assessment Division
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Branch: Biohazard Assessment Research Branch
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Product Type: Abstrct/Oral
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Presented: 10/20/1999
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Related Entries:
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Bullet Item Establish and Standardize Methodology for Detection of Waterborne Viruses from Human Sources
spacer Relationship Reason:   A Project of the Product
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