Skip common site navigation and headers
United States Environmental Protection Agency
Exposure Research
Begin Hierarchical Links EPA Home > Research & Development > Exposure Research > Publications/Presentations > End Hierarchical Links

 

Method 535: Measurement of Chloroacetanilide and Chloroacetamide Herbicide Degradates in Drinking Water By Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

spacer
spacer
Abstract:Over the past several years, ethanesulfonic acid (ESA) and oxanilic acid (OA) degradation products of acetanilide/acetamide herbicides have been found in U.S. ground waters and surface waters. The substitution of the sulfonic acid or the carbonic acid for the chlorine atom greatly increases the water solubility of degradates relative to the parent compound and contributes to the increased potential for leaching into groundwater. As a result, alachlor ESA and other acetanilide degradation products were listed on the 1998 Safe Drinking Water Act Contaminant Candidate List (CCL). One acetamide and five acetanilde herbicides are currently registered for agricultural use in the U.S. The next step in the CCL-process is to collect data on the concentrations and occurrence of these compounds in the nation's drinking water supplies. However, the existing analytical methods for measuring chloroacetanilide degradates do not address issues specific to analyzing these compounds in drinking water. Because many of the methods were developed for ground water, dechlorination was not addressed nor was the method tested in all types of drinking water matrices. In addition, existing methods do not address all twelve ESA and OA degradates of the six U.S. registered acetanilide/acetamide herbicides. Therefore, the focus of this research was to develop a sensitive and specific analytical method for the analysis of alachlor ESA and other chloroacetanilide degradates in drinking water.
spacer
Citation:Shoemaker, J. A., and M. Bassett. Method 535: Measurement of Chloroacetanilide and Chloroacetamide Herbicide Degradates in Drinking Water By Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-05/053, 2005.
spacer
spacer
Contact: Mary P. O'Bryant - (919)-541-4871 or obriant.mary@epa.gov
spacer
Division: Microbiological & Chemical Exposure Assessment Division
spacer
Branch: Chemical Exposure Research Branch
spacer
Product Type: Guidocs/Meth
spacer
Published: 05/17/2005
spacer
Downloads:
spacer
Bullet Item Method 535: Measurement of Chloroacetanilide and Chloroacetamide Herbicide Degradates in Drinking Water By Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
spacer
spacer
Related Entries:
spacer
Bullet Item Analytical Method Development for Alachlor Esa and Other Acetanilide Pesticide Transformation Products
spacer Relationship Reason:   A Project of the Product
spacer
spacer
spacer

 

ORD Home | Search EPA | Search NERL | Search EIMS | Contacts | Help

 
Begin Site Footer

EPA Home | Privacy and Security Notice | Contact Us

Last Updated on Monday, October 22, 2007
URL: http://cfpub.epa.gov