OLS : Record


Main Title Use of Genetic Activity Profiles in Hazard Evaluation.
Author Waters, M. D.; Stack, H. F.; Brady, A. L.;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC.
Publisher Nov 88
Year Published 1988
Report Number EPA/600/D-88/246;
Stock Number PB89-129415
Subjects Profiles; Hazardous materials; Mutagenicity tests; Toxicity; Carcinogens; Mutagens; Laboratory animals; Concentration(Composition); Health effects; Dibromochloropropane; Risk assessment; Propane/dibromo-chloro
Library   Call Number Additional Info Location Date Modified
NTIS PB89-129415 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/14/1989
Collation 23p
Abstract A methodology has been developed to display and evaluate multiple test quantitative information on genetic toxicants for purposes of hazard/risk assessment. Dose information is collected from the open literature: either the lowest effective dose or the highest ineffective dose tested is recorded for each agent and bioassay system. For each agent in the data base, the quantitative results from genetic and related test systems are represented by computer-generated bar graphs 'genetic activity profiles.' Bioassay systems are organized according to classes of genetic activity and subdivided by the phylogenetic level of the test organism. Genetic activity profiles were prepared 187 chemicals, e.g., dibromochloropropane, for the use of the International Agency for Research on Cancer (IARC) Working Group.
Supplementary Notes Prepared in cooperation with Environmental Health Research and Testing, Inc., Research Triangle Park, NC.
Category Codes 57Y; 57F; 68G; 44G
NTIS Prices PC A03/MF A01
Primary Description 600/11
Document Type NT
Control Number 902621854
Cataloging Source NTIS/MT
Origin NTIS
Type CAT